This report describes the sequence of events in the development and subsequent spontaneous resolution of functional tricuspid valve atresia in the donor fetus in a case of twin to twin transfusion syndrome. Fetoscopic laser coagulation of the placental anastomoses was performed at 20 weeks' gestation. Subsequently, there was evidence of increased placental vascular resistance in the donor twin ...

To evaluate the relationship of placental and amniotic fluid findings to elevated maternal serum alpha-fetoprotein (MS-AFP) levels, we compared sonograms made between 18 and 24 weeks gestational age in 76 women with elevated MS-AFP levels with sonograms of a control group. Patients with fetal malformations, incorrect dates, twins, or lack of follow-up were excluded. Overall, 27 (36%) of 76 pati...

BACKGROUND Fetal Growth Restriction is often associated with a feto-placental vascular dysfunction conceivably involving endothelial cells. Our study aimed to verify this pathogenic role for feto-placental endothelial cells and, coincidentally, demonstrate any abnormality in the nitric oxide system. METHODS Prenatal assessment of feto-placental vascular function was combined with measurement ...

The placenta is often overlooked in the routine evaluation of a normal gestation, receiving attention only when an abnormality is detected. Although uncommon, abnormalities of the placenta are important to recognize owing to the potential for maternal and fetal morbidity and mortality. Pathologic conditions of the placenta include placental causes of hemorrhage, gestational trophoblastic diseas...

Congenital anomalies have become an important cause of perinatal mortality and morbidity in both developing and developed countries. Present study was done to know the frequencies of congenital anomalies, its association with maternal diseases, maternal age and co-relation with ultrasonographic findings.Total 54 autopsy cases were studied in 6 year span from January 2007December 2012.Consent fo...

Emerging findings suggest that perinatal factors may influence the risk of developing autism spectrum disorders (ASD). Abnormal placentation has been proposed as a potential factor. We aimed to evaluate association between placental pathology and gross morphology with ASD. conducted matched case-control study children confirmed who were born 2000 2017 at one three university-affiliated hospital...

THE PERINATAL Mortality Survey has shown that deaths due to anoxia during and before labour account for 10.5 in every 1,000 deliveries (Butler and Bonham, 1963). It is believed that the majority of these intrauterine deaths are due to an abnormality of the placenta (Potter, 1961). Although in some such cases an anatomical lesion of the placenta may be found, as for example, in retroplacental ha...

Diagnosing placenta percreta can be difficult. We describe a 41-year-old woman presenting at 21 weeks' gestation with intraabdominal bleeding and no signs of placental abnormality on ultrasound. The disagreement between results of the ultrasound and magnetic resonance imaging made definitive diagnosis difficult. The bleeding resolved spontaneously after a blood transfusion, and the patient was ...

Although uncommon, abnormalities of the placenta are important to recognise owing to the potential for both maternal and fetal morbidity and mortality. The placenta is often overlooked in the routine evaluation of a normal gestation, receiving attention only when an abnormality is detected. During the formal scan to confirm a fetal death, the information gathering process to elucidate a possibl...

Gastroschisis is a congenital abdominal-wall defect that typically occurs to the right of the umbilicus. Only twenty-one cases of left-sided gastroschisis have been described in the literature. Here we report a large left-sided gastroschisis with pulmonary hypoplasia, scoliosis, ventricular septal defect and absence of gallbladder. Section of placental membranes revealed vacuolization of the am...