HIGHLIGHTS Piper aduncum L., which belongs to the Piperaceae family, is native Amazon region, Brazil. Extracts, essential oils (EOs) and compounds isolated from this species have exhibited remarkable biological activities. Its major chemical constituent definitely dillapiole, an arylpropanoid.

Abstract Giuseppe Raddi collected in the state of Rio de Janeiro, Brazil, from November 1817 to June 1818. He published 12 new names family Piperaceae an article that appeared 1828. Raddi's has not been cited specialized literature and these were never properly studied. In present study, are typified, their identity is clarified. Five combinations here presented, namely Peperomia callitrichoide...

From the methanol extract of the aerial parts of Peperomia blanda (Piperaceae), two chromenes were isolated and characterized mainly through application of 2D-NMR spectroscopy. The structures were 2S-(4-methyl-3-pentenyl)-6-formyl-8-hydroxy-2,7-dimethyl-2H-chromene and 2S-(4-methyl-3-pentenyl)-5-hydroxy-6-formyl-2,7-dimethyl-2H-chromene named as blandachromenes I and II, respectively.

The first total synthesis of laetispicine (1a), an amide alkaloid isolated from the stems of Piper laetispicum C.DC (Piperaceae), and the synthesis of some of its derivatives were described. Based on the evaluation of antidepressant activities in the forced swimming test, compounds 1h and 1i were identified as potent and safe antidepressant lead compounds.

Piper hispidinervum (C. DC.), Piperaceae, is a promising source of sassafras oil, the source of safrol, currently derived from endangered plants of the Lauraceae such as Ocotea pretios Ness (Mez.), Cinamomum petrophilum, C. mollissimum, and Sassafras albidum Nutt. The essential oil of P. hispidinervum contains high levels (83–93%) of safrole in leaves which can be easily extracted by hydrodisti...

Indian spices that provide flavor, color, and aroma to food also possess many therapeutic properties. Ancient Indian texts of Ayurveda, an Indian system of medicine, detailed the medicinal properties of these plants and their therapeutic usage. Recent scientific research has established the presence of many active compounds in these spices that are known to possess specific pharmacological prop...