775 Pilomatricoma is a benign skin neoplasm that arises from hair follicle matrix cells. It occurs on the head, neck, and upper extremities, and less frequently on the trunk and lower extremities. The etiology of pilomatricoma is subject to controversy. Trauma, insect bites, or surgery are thought to be antecedent events to the onset of the tumors. Influenza vaccination is a common annual event...

Proliferating pilomatricoma is a distinctive rare variant of pilomatricoma first described in 1997.Very few cases of proliferating pilomatricoma have been reported in the literature until date. This report is a case of 65 years old male presenting with hard nodular lump on the right side of neck slowly increasing in size for the last 8 months. Wide excision of the lump was performed with clear ...

arising from the hair matrix (1-3). The preoperative diagnosis of this entity may be difficult because of its multiple manifestations (1), especially if the examining physician is unfamiliar with them. There have been some reports in the radiological literature which included the CT (2, 4, 5) and MR (2, 6-8) imaging findings of pilomatricoma however, to the best of our knowledge, there have bee...

BACKGROUND Calcifying epithelioma of Malherbe, or Pilomatricoma, is considered an uncommon cutaneous neoplasia, normally occurring in children as a solitary, firm, asymptomatic, hard, subcutaneous, slowly growing nodule on the face, neck, or proximal upper extremity. In literature, two Pilomatricoma ultrasound patterns are described: the totally calcified nodule and the hypoechoic nodule with i...

Background: Pilomatricoma is a benign follicular tumor that is composed of basaloid cells, transitional cells and shadow cells. β-Catenin is a 92-kDa protein, and it plays important roles in cell-cell adhesion at the cell membrane and signal transduction in the nucleus. β-Catenin has recently been shown to play an important role in the formation of hair follicle-related tumors, including piloma...

Pilomatricoma, also known as calcifying epithelioma of Malherbe, is an asymptomatic, slow-growing, benign dermal neoplasm that originates from hair cortex cells. The most common sites are the head and neck (68.2%), followed by the trunk (14.4%) and the upper (15.3%) and lower (2%) extremities. The majority (60%-70%) of tumors develop in the first 2 decades of life. A typical pilomatricoma prese...

Background: Pilomatricoma, the most common hair follicle tumor, has a wide variety of clinicopathological characteristics and is often misdiagnosed. Objective: The aim of this study was to explain the clinical and histological spectrum of tumor in order to help for its better diagnosis. Patients and Methods: In a retrospective descriptive study, the clinical and histological features of pilomat...