background : animal models have been proven useful in elucidating the details of interaction between pathogenic bacteria and their human hosts, in addition to assessing the efficacy of therapeutic compounds and vaccines. in this study, we investigate the colonization of helicobacter pylori ( h. pylori ) in experimentally-infected guinea pigs over a six-month period. materials and methods: a bac...

Previous studies indicate that Matricaria chamomilla (MC), a folk remedy plant, is very useful in the treatment of spasmogenic bowel diseases but the way of its action is not clear. For this purpose, we studied the effect of MC extract on the electrically activation in Guinea-Pig ileum in an invitro model. We used guinea pig in this study. After of kill, we brouhght out a piece of ileum and fix...

esophagus having different tissues has a special role in the gastrointestinal tract. among different species, layers of the esophagus, have a substantial difference. also, diameter of esophagus varies in different parts of it.the information of histological structure of rabbit and guinea pig esophagus is still incomplete. therefore, the present study was conducted. therefore, for review and com...

the enterotoxins (ets) of clostridium perfringens isolated from enterotoxemic or diarrheic alpacas, pigs, calves, dogs, and horses were obtained from sporulated cell extracts. the ets from alpaca, pig, and calf isolates were chromatographed on sephadex g-loo. monoclonal antibodies (mabs) against ets derived from alpaca, pig, and calf c. perfringens isolates were produced. the mabs were used in ...

Onion (Allium Cepa) contains high levels of flavonoids. Although there are many studies indicating the inhibitory effects of flavonoids on xanthine oxidase, there is no report on the effect of onion on this enzyme. Therefore, in the present study, the inhibitory effects of onion on xanthine oxidase are investigated. Fresh filtered juice of onion was prepared and its inhibitory effect on guine...

In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both...

several therapeutic effects including diuretic, anti-pyretic and anti-scurvy have been reported for portulaca oleracea. in previous studies the analgesic, anti-inflammatory, anti-hypertensive, anti-oxidant, muscle relaxant effects and neuropharmacological effects of the aqueous extract of portulaca oleracea have been demonstrated on experimental animals. in the present study the antitussive eff...

objective(s) in the present study, the differences in the relaxant effects of aqueous, ethyl acetate and n-butanol fractions of rosa damascena on tracheal smooth muscle of guinea pigs were examined. materials and methods the relaxant effects of three cumulative concentrations of each fraction (0.1, 0.2 and 0.4 g%) in comparison with saline and three cumulative concentrations of theophylline (0....

objectives: cow urine ark (cua), known as “amrita” as mentioned in ayurveda, contains‎ anti-hyperglycemic and antioxidant effects. therefore, we designed the present study to evaluate the lipid ‎lowering activity of cua and its possible implication in metabolic syndrome.‎ materials and methods: thirty guinea pigs of either sex were divided into five groups: group 1 and 2 serving as a vehicle ‎a...

foot-and-mouth disease (fmd) is a severely contagious viral disease that mainly affects cloven-hoofedlivestock and wildlife. this study quantifies the cytokines mrna expression of vaccinated guinea pigs withfmd type o inactivated vaccine. blood samples were collected from eight guinea pigs at 7 and 28 days after thefirst vaccination. extracted mrnas were reverse-transcribed into cdna and analyz...