Purpose: Rose Bengal (RB) is a potential photodynamic sensitizer in anticancer therapy. The purpose of this study was to prepare multivesicular liposomes (MVL) loaded with RB to enhance its photostability and intracellulaer photodynamic efficacy. Methods: Four MVL-RB formulations were prepared by reverse phase evaporation technique using a double emulsion method. The photostability of RB in pho...

BACKGROUND Drugs photostability plays two different opposite roles; a real advantage arises considering the longer expiration time of the drugs while the consequent persistence in the environment involves an obvious negative effect bound to their harmfulness.On this basis we tested the photostability and toxicity of three pharmaceutical active principles: Finasteride, Diclofenac and Naproxen. T...

Ultrasensitive detection and real-time monitoring of biological processes can benefit significantly from the improved brightness and photostability of the popular organic dyes such as cyanines. Here, using a model cyanine dye, Cy3, we demonstrate that brightness and photostability of the dye is significantly altered when trapped in a molecular container, e.g. cucurbit[n]urils (CB[n]) and cyclod...

The intrinsic photostability characteristics of pharmaceutical active substances and medicinal products should be evaluated to demonstrate that, as appropriate, light exposure does not result in unacceptable change. The photostability of Finasteride, Diclofenac and Naproxen was studied. The irradiation of the samples was performed according to the conditions suggested by the ICH Guidelines [1] ...

The content of methylammonium dominates the photostability tin–lead perovskite solar cells.

Merocyanine dyes have proven valuable for live cell fluorescence imaging applications, but many structures have been limited by rapid photobleaching. We show that photostability is substantially enhanced for merocyanines having a cyano group at a specific position in the central polymethine chain. Evidence is presented that this is due to reduction in reactivity of the dyes with singlet oxygen....

We report an optical technique that yields an enhancement of single-molecule photostability by greatly suppressing photobleaching pathways which involve photoexcitation from the triplet state. This is accomplished by dynamically switching off the excitation laser when a quantum jump of the molecule to the triplet state is optically detected. The resulting improvement in photostability unambiguo...

The recent surge in interest in the metal-enhanced fluorescence MEF phenomenon and its numerous applications in the biosciences has fueled research into identifying alternative metals to silver which have desirable properties, such as enhanced emission and fluorophore photostability. In this paper, we subsequently study and reveal that tin nanodeposits are a suitable metal for MEF with an elect...