BACKGROUND Solar urticaria (SU) is an uncommon photodermatosis characterized by erythema and whealing within minutes to a few hours after exposure to sunlight or an artificial light source. OBJECTIVE To determine the clinical features, photobiological characteristics and treatment outcomes in Thai SU patients visiting a tertiary referral hospital. METHOD A retrospective analysis of 13 patie...

Polymorphous light eruption is classified as an immune-mediated photodermatosis. It the most common cause of photosensitivity in children between 6 and 14 years old. characterised by pruritic or tingling erythematous papular plaque lesions sunlight-exposed skin which occur spring early summer. The first signs polymorphous typically appear several hours to days after exposure intense sunlight ta...

BACKGROUND Actinic prurigo (AP) is an idiopathic photodermatosis, this entity requires exposure to UV-B and -A to develop lesions. Apoptosis is a physiological death program that can be initiated by a permanently active mechanism (extrinsic pathway) or irreparable damage (intrinsic pathway). MATERIAL AND METHODS Descriptive study, the sample size comprised 64 paraffin blocks of tissue with a ...

Chronic urticaria (CU) is a skin condition characterized by the presence of intensively pruritic lesions occurring intermittently or continuously for more than 6 weeks. Because the cause(s) of CU are often not known, it is usually referred as chronic spontaneous urticaria (CSU) or chronic idiopathic urticaria (CIU). It affects 0.1%–0.3% of children. Moreover, solar urticaria (SU) is a rare chro...

The aim of this paper is to present the state of knowledge on cutaneous neurogenic inflammation. Peripheral effector functions served by afferent sensory neurons underlie the so-called neurogenic inflammation. The mechanism of cutaneous neurogenic inflammation is connected with the release of neuropeptides from the sensory endings. They also exert a number of functions within the immune system....

BACKGROUND Actinic prurigo (AP) is an idiopathic photodermatosis. Although its initial manifestations can appear in 6 to 8-year-old children, cases are diagnosed later, between the second and fourth decades of life, when the injuries are exacerbated. OBJECTIVE To identify risk factors associated with clinical manifestations of AP such as skin and mucosal lesions. METHODS Thirty patients wit...

Photoallergic dermatoses are skin lesions following sun exposure, characterized by activation of immunological mechanisms, involving photosensitizers and photoallergens that can cause photosensibilization in some individuals. In this group of disorders, photoallergic contact dermatitis should be accentuated. It manifests as contact allergic dermatitis on sun-exposed skin areas, following direct...

Endothelial leukocyte adhesion molecule-1 (ELAM-1), vascular cell adhesion molecule-1 (VCAM-1), and intercellular adhesion molecule-1 (ICAM-1) are cytokine-regulated cell-surface leukocyte adhesion molecules. We have investigated the in vivo kinetics and pattern of expression of these adhesion molecules in relation to tissue accumulation of leukocytes in the photodermatosis, polymorphic light e...