background: zoonotic cutaneous leishmaniasis (zcl) due to leishmania major is increasing in many parts of iran. this disease originally is a disease found in gerbils. leishmania parasites are transmitted by sandflies that live and breed in gerbil burrows. nested pcr amplified leishmania its1-5.8s rrna gene in both main reservoir host “rhombomys opimus” and in the “phlebotomus papatasi” main vec...

The repellent action of neem oil was evaluated against sand flies under laboratory and field conditions. Concentrations of 2% neem oil mixed in coconut or mustard oil provided 100% protection against Phlebotomus argentipes throughout the night under field conditions; against Phlebotomus papatasi it repelled sand flies for about 7 h in the laboratory. Neem oil is an indigenous product and a low-...

following an epidemiological survey of zoonotic cutaneous leishmaniosis (zcl) in some villages of badrood, a rural district north of the city of natanz, central iran, phlebotomus (phlebotomus ) papatasi scopoli were found to be naturally infected with leishmania (leishmania) major zymodeme mon-26. sandflies were collected and dissected biweekly from rodent burrows during sandfly season, april- ...

Cutaneous leishmaniasis is one of the most important vector-borne endemic diseases in Turkey. The main objective of this study was to evaluate the influence of temperature on the developmental rates of one important vector of leishmaniasis, Phlebotomus papatasi (Scopoli, 1786) (Diptera: Psychodidae). Eggs from laboratory-reared colonies of Phlebotomus papatasi were exposed to six constant tempe...

BACKGROUND The saliva of sand flies strongly enhances the infectivity of Leishmania in mice. Additionally, pre-exposure to saliva can protect mice from disease progression probably through the induction of a cellular immune response. METHODOLOGY/PRINCIPAL FINDINGS We analysed the cellular immune response against the saliva of Phlebotomus papatasi in humans and defined the phenotypic character...

Cutaneous leishmaniasis (CL) is a neglected clinical form of public health importance that is quite prevalent in the northern and eastern parts of Egypt. A comprehensive study over seven years (January 2005-December 2011) was conducted to track CL transmission with respect to both sandfly vectors and animal reservoirs. The study identified six sandfly species collected from different districts ...

Background: Geographical distribution of zoonotic cutaneous leishmaniasis (ZCL) has continuously been extended in recent years in Iran. The Beiza District is one of the newly-emerged endemic foci of ZCL in southern Iran. The main aim of the present study was to detect the vector(s) of ZCL in this area. Methods: To detect the fauna and vectors of ZCL in this district, sand flies were cau...

background : zoonotic cutaneous leishmaniasis (zcl) is a neglected tropical disease prevailed in many rural areas of 17 out of 31 provinces in iran. the main vector of the disease is phlebotomus papatasi and the causative agent is leishmania major in zcl foci of iran. in the current study we investigated the validity of accessory glands secre­tions as an indicator to recognize parous from nulli...

conclusions this is the first molecular report on parasite infection of both vector (p. papatas) and reservoir (t. indica) to l. major from this area. therefore, the population of both sandflies and rodents should be reduced using control methods. background leishmaniais which is one of the six most important tropical diseases in the world are in iran in 3 forms. cutaneous leishmaniasis (cl) is...

Topical application of 2% neem oil mixed in mustard oil provides 86.1% protection for about 7 hours against the bite of Phlebotomus papatasi (Scopoli) under laboratory conditions (Sharma and Dhiman, 1993). One ml of 5% neem oil in acetone applied to cardboard mats when used on electric heating device marketed for use for synthetic pyrethroid mats, have been reported 100% effective as space repe...