The present study is aimed to evaluate the chemical characterization and antimutagenic potential of propolis extracted in three different solvents (ethanol, polyethylene glycol water). properties extracts were identified using HPLC-DAD LC?MS/MS extract found be richer than ethanolic water considering composition. In addition, activities determined Ames assay. concentrations 3, 1.5 0.75 mg plate...

We investigated the antimutagenic activities and chemical compositionsof essential oil (EO) from Melissa officinalis, Lavandula angustifolia Origanum onites plants belonging to Lamiaceae family. The compositions of were determined by GC/MS analysis Ames assay was used in activity analysis. Citral, linalool, thymol terpinenes major components EOs M. L. O. onites. In assay, it that EO officinalis...

Results Total of 153 patients with contact dermatitis were enrolled. Each patient was patch tested using (TRUE Test). The patch was removed after 48 hours and read after 96 hours. A positive reaction was scored according to the standard scoring system recommended by the international group. Mean age was 39.9 (SD 13.84) years old. Females were 78 ( 51%). Majority were Kuwaiti patients 76.5%. Occ...

Immature dendritic cells (DCs) modulate differentiation markers following in vitro exposure to chemicals generating contact allergies. THP-1 is a monocytoid cell line maintaining some differentiating plasticity. In this study, human DCs and THP-1 cells were compared as in vitro models to predict contact sensitisation of chemicals with different sensitising potential. Expression of CD80 and CD86...

A series of new di-, tri-, and tetranuclear Co(II) and Cu(II) complexes of three new diSchiff base ligands were synthesized by two different methods. The first method involved the synthesis of the three ligands from condensation reaction of 3,4-dihydroxybenzaldehyde (L'H2) with ethylenediamine (en), o-phenylenediamine (o-PD), or 4,5-dimethyl-1,2-phenylendiamine (DMPD) in a mole ratio of 2 : 1 f...

BACKGROUND AND AIMS Elimination of allergens/topical medications causing contact dermatitis in venous eczema, which poses a significant problem in its chronicity and treatment, provides the basis for better therapeutic outcome. Our objective was to determine the pattern of contact sensitization in venous eczema patients in Himachal Pradesh (India). METHODS Thirty-four patients (M:F, 31:3) and...