Objectives—To determine in this pilot study whether aerobic exercise aVects phenylacetic acid concentration in the urine. Methods—Twenty healthy men provided 24 hour urine samples on two consecutive days for the determination of phenylacetic acid levels. Before and during day 1, subjects refrained from physical activity; on day 2 subjects ran on a treadmill at 70% of their maximal heart rate re...

BACKGROUND 2-Phenylethylamine is an endogenous amine, which acts as a neuromodulator of dopaminergic responses. Exogenous 2-phenylethylamine is found in certain foodstuffs and may cause toxic side-effects in susceptible individuals. MATERIALS AND METHODS The present investigation examined the metabolism of 2-phenylethylamine to phenylacetic acid, via phenylacetaldehyde, in freshly prepared an...

A number of Pseudomonas strains accumulated polyhdroxyalkanoate (PHA) from a variety of aromatic hydrocarbons. In many strains the level of PHA accumulation was dependent on the side chain length of the phenylalkanoic acid provided for growth. 4 of the 8 strains accumulated increased levels of PHA as the side chain length of the phenylalkanoic acid substrate increased. PHA accumulated from styr...

Meldrum's acid, 2'5-diphenyl-1'3-dioxane-4'6-dione, was produced by [2+2] cycloadditions of the (chlorocarbony1)phenylketene with benzaldehyde. Acid hydrolysis of the meldrum's acid regenerated benzaldehyde and also yielded phenylacetic acid as the final product

This paper describes an eco-friendly and efficient direct amidation of benzylamine and phenylacetic acid derivatives in the presence of 10 mol% NiCl2 as catalyst without any drying agent. For the different phenylacetic acid and benzylamine derivatives, the direct catalysed amidation gave moderate-to-excellent yields in toluene. The steric and electronic effects of substituent groups on the phen...

Penicillium chrysogenurn Q-176に よPhenylacetic Acidの 酸化的代謝 に關す る研 究(第6報) Pen. chyysognum Q-176 の1変 異 種 に よ るHomogentisic Acidの 生成 に つ い て (そ の2)Phenylacetic Acid代 謝 異 常 菌 株 の菌 学 的性 質 磯 野 正 雄(武田 薬品工業株式会社大阪工場) 昭 和28年10月24日 受 理 Oxidative Metabolism of Phenylacetic Acid by Penicillium chrysogenum Q-176. Part 6. The Production of Homogentisic Acid by a Mutant Strain Induced from Pen. chrysogenum Q-17...