نتایج جستجو برای: pge2 سرمی
تعداد نتایج: 11548 فیلتر نتایج به سال:
این تحقیق به منظور ارزیابی میزان فنل و فلاونویید کل، عملکرد آنتیاکسیدانی، اثر ضددردی و ضدالتهابی عصاره گیاه دارویی ریحان بنفش ( basillicum var. purpurescens.Ocymum) بر موشهای صحرایی نر در مقایسه با داروهای اپیوئیدی (مرفین) انجام گرفت. در این مطالعه از موشهای صحرایی نرنژاد ویستاردرمحدوده وزنی250±10 گرم استفاده گردید. بهصورت تصادفی موشها به پنچ گروه ده تایی تقسی...
Background: Bone resorption is one of the main features of inflammatory periapical lesions and is mainly mediated by interleukin-1 beta (IL-1β), tumor necrosis factoralpha (TNF-α) and prostaglandin-E2 (PGE2). Recent investigations of these lesions revealed that pharmacological modulation may be possible. Objective: The aim of this study was to evaluate the effect of Ibuprofen on IL-1β, TNF-α an...
Effects of intracerebroventricularly (i.c.v.) injected PGE2 and PGF2alpha on the urine outflow were studied in ethanol-anesthetized rats. PGE2 and PGF2alpha, when injected i.c.v., caused diuresis which was followed by antidiuresis. Phentolamine, when perfused i.c.v., was an antidiuretic and inhibited the diuretic and antidiuretic effects of PGE2. Diphloretin phosphate inhibited both effects of ...
زمینه و هدف: اهمیّت اسیدهای چرب غیر اشباع امگا 3 در رژیم غذایی و نیز اثرات ضدّ التهابی آن مشخص شده است. لذا، هدف این پژوهش، بررسی تأثیّر مصرف اسید چرب امگا 3 و تمرینات بی هوازی بر تغییرات سطوح پلاسمایی، پروستاگلاندینE2(PGE2)CK, LDH, در زنان فعّال است. مواد و روشها: این پژوهش از نوع نیمه تجربی با اندازهگیری مکرّر میباشد که در آن 32 دانشجوی تمرین کرده (با میانگـــین سن 3/0±41/22 سال، میانگین ق...
Objective(s): Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer’s and various cancer. Indonesian cassia (Cinnamomum burmanni C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine es...
The mechanism by which prostaglandin E2 (PGE2) inhibits sodium absorption (JNa) in the rabbit cortical collecting duct (CCD) was explored. PGE2 activates at least three signaling mechanisms in the CCD: (a) by itself PGE2 increases cAMP generation (b) PGE2 also inhibits vasopressin-stimulated cAMP accumulation, and (c) PGE2 raises intracellular calcium([Ca++]i). We tested the contribution of the...
We hypothesized that prostaglandin E2 (PGE2) stimulates amniotic fluid transport across the amnion by upregulating vascular endothelial growth factor (VEGF) expression in amnion cells and that amniotic PGE2 concentration correlates positively with intramembranous (IM) absorption rate in fetal sheep. The effects of PGE2 at a range of concentrations on VEGF 164 and caveolin-1 gene expressions wer...
Staphylococcus aureus is a major pathogen of varieties of oral mucous infection. Prostaglandin E2 (PGE2) is a pro-inflammatory factor and Cyclooxygenase 2 (COX-2) is a critical enzyme of PGE2 biosynthesis. The purpose of this study is to investigate whether Staphylococcus aureus can increase PGE2 production of oral epithelial cells and how PGE2 functions in the growth and adherence of Staphyloc...
Although the exact mechanism of prostaglandin E2(PGE2)-mediated cytoprotection has not been elucidated, its ability to induce cytoprotection in cell culture suggests this action occurs at the cellular level. The present studies were conducted to determine whether PGE2 induces protection against 2,3,5-(trisglutathion- S-yl)-hydroquinone [2,3,5-(trisglutathion- S-yl)-HQ]-mediated cytotoxicity in ...
BACKGROUND The ovulatory gonadotropin surge increases synthesis of prostaglandin E2 (PGE2) by the periovulatory follicle. PGE2 actions on granulosa cells are essential for successful ovulation. The aim of the present study is to determine if PGE2 also acts directly at the oocyte to regulate periovulatory events. METHODS Oocytes were obtained from monkeys and mice after ovarian follicular stim...
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