The complexity and the astronomic number of possible chemical mixtures preclude any systematic experimental assessment of toxicology of all potentially troublesome chemical mixtures. Thus, the use of computer modeling and mechanistic toxicology for the development of a predictive tool is a promising approach to deal with chemical mixtures. In the past 15 years or so, physiologically based pharm...

We used molecular methods and population genetic analyses to study the effects of chronic contaminant exposure in marsh frogs from Sumgayit, Azerbaijan. Marsh frogs inhabiting wetlands in Sumgayit are exposed to complex mixtures of chemical contaminants, including petroleum products, pesticides, heavy metals, and many other industrial chemicals. Previous results documented elevated estimates of...

Polar petroleum components enter marine environments through oil spills and natural seepages each year. Lately, they are receiving increased attention due to their potential toxicity to marine organisms and persistence in the environment. We conducted a laboratory experiment and employed state-of-the-art Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) to characterize the...

Current research of complex chemical systems, including biomass pyrolysis, petroleum refining, and wastewater remediation requires analysis of large analyte mixtures (>100 compounds). Quantification of each carbon-containing analyte by existing methods (flame ionization detection) requires extensive identification and calibration. In this work, we describe an integrated microreactor system call...

Data on the chemistry of biologically active components of petroleum, synthetic fuel oils, certain metal elements and pesticides provide valuable generic information needed for predicting the long-term fate of buried waste constituents and their likelihood of entering food chains. Components of such complex mixtures partition between solid and solution phases, influencing their mobility, volati...

Chemical characterisation of contaminant mixtures is important for environmental forensics and risk assessment. The great challenge in future research lies in developing suitable, rapid, reliable and objective methods for analysis of the composition of complex chemical mixtures. This thesis describes the development of such methods for assessing the identity (chemical fingerprinting) and fate (...

Values of some characteristic parameters of confined explosions for LPG (Liquefied Petroleum Gas)-air quiescent mixtures are examined in correlation with the initial pressure of fuel-air mixture and fuel/air ratio. The explosion pressures, the explosion times and the maximum rates of pressure rise were obtained from experiments made at ambient initial temperature in two closed vessels with cent...

Several very serious accidents in laboratories have resulted from the use of flammable liquids, such as volatile petroleum distillates, or toluene, to form the bath of a cryostat. In some instances explosions have occurred, and burning liquid has been thrown upon the operator. The purpose of the investigation has been to find liquids that will not burn, that have very low freezing points, and t...