PURPOSE We assessed the radiographic changes of the acetabulum during the course of Perthes' disease and investigated whether they were associated with femoral head sphericity 5 years after diagnosis. METHODS We studied 123 children with unilateral Perthes' disease, femoral head necrosis more than 50 % and age at diagnosis 6 years or older. Pelvic radiographs were taken at onset, 1 year and 5...

Synonyms for this disease include “avascular necrosis of the femoral head” and “aseptic necrosis of the femoral head”, “Perthes disease” and “Legg Perthes” disease, “osteochon-dritis”, “coxae juvenilis”, “coxa plana” and “idiopathic osteosis”. The terms “avascular/aseptic necrosis of the femoral head” are also used to describe a process of femoral head necro-sis in dogs following traumatic frac...

Perthes' disease (Legg-Calvé-Perthes' disease) is relatively common in childhood, affecting 0.8/100.000 children. Late onset Perthes' disease, older than 8 years of age, constitutes about 20% of cases and is known for its aggressive course and poor outcome with chronic hip pain and stiffness. Although containment of the head in the acetabulum is the usual treatment for early cases, its results ...

Six boys were examined during the second year of life, each with symptoms in one hip. The affected femoral capital epiphysis was smaller or more irregular (or both) than that of the unaffected hip but was neither subluxed nor dislocated. The subsequent radiographs revealed changes similar to those in severe Perthes' disease. Nevertheless, we give reasons for believing that this disorder in boys...

It has recently been postulated that thrombophilia may have a role in the aetiology of Perthes' disease. The published reports, however, remain conflicting. In this study a retrospective analysis of the coagulation parameters was made in 47 patients with Perthes' disease and the results compared with the clinical data. Five patients with Factor V Leiden mutation were found (10.6%) and surprisin...

Retroversion of the adult acetabulum following a previous Legg-Calvé-Perthes disease (LCPD) is found in 30-40% of the patients. It is known that in LCPD there may also be morphologic changes in the nonaffected controlateral acetabulum. We investigated the prevalence of retroversion of the contralateral acetabulum in a group of adult patients with a history of LCPD. We found this morphology in 1...

It has been suggested that Perthes' disease is more prevalent in urban areas, and that the risk increases with deprivation. We present the findings of a preliminary analysis of Perthes' disease in Northern Ireland, which is shown to have one of the highest national annual rates of incidence in the world (11.6 per 100000). Of the 313 children diagnosed over a seven-year period, 311 were allocate...

It has been shown that in the puppy, two infarcts separated by an interval of four weeks produce a disorder of long duration which results in flattening and broadening of the femoral head and which reproduces the radiological changes seen in Perthes' disease in man. The histological appearances produced by two infarcts are characteristic. In this study the histological appearance of fifty-seven...

Aim. To develop an animal model of femoral head aseptic necrosis for studying Legg–Calvé–Perthes disease. Materials and Methods. induce the development necrosis, we used Wistar rats (n = 8) which suffered from combined hypoperfusion increased intra-articular pressure in hip joint. Having employed isoflurane anesthesia, performed incision (≈ 3 cm length) on outer surface thigh projection joint t...

About a hundred years after the first reports about the disease Legg-Calvé-Perthes that Perthes also called, since it is still the main cause of this disease is unknown. Perthes with the loss of femoral head blood flow in growing children, between the ages of 2-13 years is determined and is considered as a vascular disease. The outbreak, one in every 1,200 children younger than 15 years is. 5-4...