The use of classic antipsychotic drugs is limited by the occurrence of extrapyramidal motor symptoms, which are caused by dopamine (DA) receptor blockade in the neostriatum. We examined the impact of early-life stress on haloperidol-induced catalepsy using the rat model of prenatal restraint stress (PRS). Adult "PRS rats," i.e., the offspring of mothers exposed to restraint stress during pregna...

OBJECTIVES To describe a modification of the index of clinical consequences of untreated dental caries [pulpal involvement, ulceration, fistula and abscess (PUFA/pufa) index] to pulpal involvement-roots-sepsis (PRS/prs) and to compare the two indices using the example of caries in primary molar teeth in children aged 6-8 years. SUBJECTS AND METHODS The study sample included 542 children aged ...

Startling acoustic stimuli (SAS) induce the early release of prepared motor responses. The current study used SAS, in conjunction with a classical conditioning paradigm, to examine advanced motor preparation of conditioned postural responses (PRs). After generalized startle responses were induced, standing posture was perturbed in 2 blocks of 15 Conditioning trials, where in each trial the onse...

Product Range Specification (PRS) in the automotive world is one of the most complex PRS that exists in industrial contexts. PRS plays therefore a key role in the information system of an automaker: related data pervades many systems, and numerous applications are using it. This is the case at Renault, where PRS is modelled as a Constraint Satisfaction Problem. In this paper, we study how to re...

Although software agents are becoming more widely used, methodology for constructing agent programs is poorly understood. In this paper, we take a step towards specifying and proving correctness for a class of agent programs based on the PRS architecture, Georgeff and Lansky (1987), one of the most widely used in industrial settings. We view PRS as a simplified operating system, capable of runn...

The Procedural Reasoning System (PRS) is the best established agent architecture currently available. It has been deployed in many major industrial applications, ranging from fault diagnosis on the space shuttle to air traffic management and business process control. The theory of PRS-like systems has also been widely studied: within the intelligent agents research community, the beliefdesire-i...

Sexual communication in moths offers a simplified scenario to model and investigate insect sensory perception. Both PBPs (pheromone-binding proteins) and PRs (pheromone receptors) are involved in the detection of sex pheromones, but the interplay between them still remains largely unknown. In this study, we have measured the binding affinities of the four recombinant PBPs of Chilo suppressalis ...

Results 48 clinicians (35 dms, 13 prs) from across the UK responded. At time of survey response, dms reported managing a mean 4.2 CYP with JLS; prs 17.9. 26% dms managed all CYP in collaboration (with a PR, paediatrician, adult rheumatologist or another DM) whilst 31% prs managed all CYP in collaboration (with a DM or paediatrician). 43% of dms and 91% prs reported formal transition arrangement...

background: the accurate results of the individual doses in personal dosimety which are reported by the service providers in personal dosimetry are very important. there are national / international criteria for acceptable dosimetry system performance. objective: in this research, the sources of uncertainties are identified, measured and calculated in a personal dosimetry system by tld. method:...