Urogenital infection with Chlamydia trachomatis can lead to development of an acute inflammatory arthritis, and this acute disease becomes chronic in some individuals. Research indicates that the organism is present in synovial tissue of patients with chronic disease in a persistent, rather than an actively growing, form. Importantly, metabolic and other characteristics of persistent Chlamydia ...

AIMS To examine the effectiveness of a management protocol for childhood epiphora using a joint ophthalmological and otolaryngological team approach. METHOD A temporally defined retrospective study of 70 children (92 eyes) undergoing surgery for persistent epiphora, despite two previous technically successful probing procedures. All the operations involved a joint approach involving a paediat...

BACKGROUND Serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are important tests in the initial diagnosis of periprosthetic joint infection. Many surgeons also use these tests to determine if infection has resolved between stages of a 2-stage procedure, but little data exist regarding this practice. METHODS A retrospective review of our institutional total joint database...

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease characterised by persistent inflammation of synovial joints, often leading to joint destruction and disability. The major goals of treatment are to relieve pain, reduce inflammation, slow down or stop joint damage, prevent disability, and preserve or improve the patient's sense of wellbeing and ability to function.

Introduction Juvenile idiopathic arthritis (JIA) is the most common chronic pediatric rheumatic disease, affecting 4 of every 1,000 children worldwide. It may cause joint damage, persistent pain and retardation of normal growth, which eventually may lead to long-term disability and decreased quality of life. Treatment aims disease control and induction of remission, preventing joint damage and ...

Persistent postsurgical pain is a prevalent but underacknowledged condition. The aim of this study was to assess the prevalence, sensory qualities, and postoperative determinants of persistent pain at 3 to 4years after total knee replacement (TKR) and total hip replacement (THR). Patients completed a questionnaire with included the Western Ontario and McMaster Universities Index of Osteoarthrit...

Background/objective: Despite the present routine treatment of septic arthritis with antibacterial agents, articular damage is persistent and frequently leads to loss of joint function.  The aim of this study was to assess the effect of intra-articular corticosteroids added to systemic antibiotics in the treatment of experimental staphylococcal knee joint infection in rabbits. Methods: Thirty r...