Purpose: To evaluate the inflammatory response in the choroid, retina and vitreous in rabbit eyes underwent cryotherapy followed by intravitreal triamcinolone acetonide and to compare with those underwent cryotherapy followed by intravitreal injection of saline solution. Methods: This is a prospective case-control study. Surgical procedures were performed in eleven rabbits. Two animals were exc...

The penetration of objects into the orbit can lead to blindness and even to the death of the patient. The penetration of organic objects longer than 7 cm into the eye is a rare phenomenon. In this study, we report a case in which a 6-year-old boy fell on a pencil which penetrated the upper side of his right eye orbit. Because of the agitation of the child and the lack of access, it was not poss...

PURPOSE To investigate the response of the retina to an ischemic insult, we measured the levels of glutamate in the vitreous of rabbit eyes. METHODS Ocular ischemia was induced in the vitreous of rabbit eyes by simultaneous ligature of the optic nerve, ciliary arteries, and extraocular muscles for 45 minutes. Contralateral eyes were subjected to a conjunctival peritomy to serve as sham-operat...

Introduction: To determine the distance of Extraocular Muscle (EOM) insertions to limbus in Iranian people. Materials and Methods: 173 cases (173 eyes) were entered in an observational cross-sectional study. Patients referred to the Khatam-al-Anbia Hospital were included. All of them had to be operated on specific indications. After 360 peritomy in the operating room, the distance between EM in...

INTRODUCTION The management of Mooren's ulcer can be a challenge for clinicians. OBJECTIVE To report a case of Mooren's ulcer treated with amniotic membrane transplantation supplemented with autologous serum eye drops. CASE REPORT A 22-year-old male presented with history of pain, redness, watering and diminution of vision of the right eye for one year. Examination of his eyes revealed the ...

PURPOSE To investigate the efficacy of L-carnitine in preventing retinal injury followed by ischemia-reperfusion. METHODS The eyes of 34 guinea pigs were used in this experiment. The guinea pigs were divided into two groups: the first group (n=17) was given L-carnitine intraperitoneally (500 mg/kg) and second group (n=17) received the same dose of saline solution. Under general anesthesia, pe...

The treatment of trachoma?which brings about total blindness and disfigurement in quite a number of people?has been greatly simplified after the advent of this drug. The whole medical treatment for it boils down to painting of the lids with 30 per cent sodium sulphacetamide?soluble?solution twice a day and applying 6 per cent ointment thrice a day. A course of sulpha-triad for ten days is very ...

OBJECTIVE To evaluate the feasibility and safety of enzymatic sclerostomy as a new modality to lower intraocular pressure in patients with open-angle glaucoma. METHODS This single-center, prospective, noncomparative, interventional case series included 15 blind symptomatic eyes of 15 patients with primary open-angle glaucoma. Enzymatic sclerostomy was performed with the patient under topical ...

PURPOSE To determine the corneal regenerative capacity of sequentially generated primary, secondary, and tertiary limbal explant outgrowths in a limbal stem cell deficiency (LSCD) surgical model. METHODS Two-millimeter-long limbal shallow biopsies were surgically excised from the upper quadrant of the right eye of rabbits and set on preserved amniotic membrane for explant culture. After the g...

purpose: to compare the success rate of mitomycin-c versus bevacizumab for prevention of bleb failure following phacotrabeculectomy. method: in this study 74 eyes of 69 patients with uncontrolled iop, progressive visual field loss and cataract were randomized in two groups. in the first group, after conjunctival peritomy at the sclera flap site, sponge pats soaked in mitomycin c with concentrat...