In metazoan cells, the heterochromatin is generally localized at the nuclear periphery, whereas active genes are preferentially found in the nuclear interior. In the present paper, we review current evidence showing that components of the nuclear lamina interact directly with heterochromatin, which implicates the nuclear lamina in a mechanism of specific gene retention at the nuclear periphery ...

MIHAI CUCURINGU, PUCK ROMBACH, SANG HOON LEE and MASON A. PORTER 1Department of Mathematics, UCLA, Los Angeles, CA, USA emails: [email protected], [email protected] 2Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, UK email: [email protected] 3School of Physics, Korea Institute for Advanced Study, Seoul, Korea email: lshlj82@...

Based on the analysis of articles published in theater periodicals Holy Roman Empire, thisstudy explores enlightened cultural and symbolic geographies as reflected late eighteenth-centuryGerman theatrical press. Larry Wolff has shown that western travelers tend to locate borders civilizedEurope Habsburg lands situated east Vienna, namely Galicia Hungary. If periodicalsand travel memoirs by shar...

PURPOSE Forkhead box P3 (Foxp3) is known as the most specific marker for regulatory T lymphocytes, which play an important role in immune tolerance to disturb antitumor immunity. The present study aimed to investigate the prognostic significance of Foxp3 regulatory T lymphocyte (Foxp3 Treg) infiltration in breast cancer. METHODS Immunohistochemical studies with Foxp3, CD4, and CD8 were perfor...

This study explores the spatial inequality of job accessibility in urban China, focusing on geographical skills mismatch Shanghai. Our results suggest that should be a critical concern measuring because villages create residential sites for low-skill workers central Based index considering mismatch, floating population has high periphery area there are affordable housing prices. The distributio...

BACKGROUND Adrenal venous sampling serves as a discrimination between uni- and bilateral forms of primary aldosteronism (PA). Even correctly performed adrenal venous sampling may lead to non-diagnostic results in some cases. RESULTS We describe 7 subjects with PA in whom correct cannulation of adrenal veins (high selectivity index defined as cortisol((adrenal))/cortisol((periphery)) ratio) wa...