A case of palmoplantar hyperkeratosis with periodontosis and a history of recurrent severe pyoderma, pneumonia and multiple liver abscesses is described in a 12 year old girl. The patient demonstrated neutrophil dysfunction characterized by decreased random migration and chemotaxis and defective bactericidal activity. The exact immunopathological mechanism for susceptibility to infections i...

Aim: To apply the Lamendin et al. (1992) technique on a Brazilian sample to assess its accuracy on this specific population. Methods: The authors present two measurements in single-rooted teeth: the peridontosis and transparency of the root. Then, these variables are inserted in an equation to estimate the individual’s age. The sample comprised 49 teeth obtained from the collection of the Foren...

Papillon-Lefèvre syndrome is a rare autosomal recessive disorder caused by cathepsin C gene mutation leading to the deficiency of cathepsin C enzymatic activity. The disease is characterized by palmoplantar hyperkeratosis, periodontopathy and precocious loss of dentition, and increased susceptibility to infections. Pyogenic liver abscess is an increasingly recognized complication. Three cases o...

(-)-Epigallocatechin-3-O-gallate (EGCG), present in green tea, exhibits antioxidant and antiallergy effects. EGCG3″Me, a 3-O-methylated derivative of EGCG, has been reported to show similar biological functions; the inhibitory activity of EGCG3″Me in a mouse allergy model was more potent than that of EGCG, probably due to the efficiency of absorption from the intestine. However, the functional ...

Background: Age can be estimated from the teeth by various methods like eruption of which is known tobe a good indicator age person.Aims & Objectives: The current study aimed to estimate chronological physiological changes(Modified Gustafson’s method) occurring in and also find out effect diet, other habits andsocio demographic factors on changes teeth.Materials Method: Present was done usi...

Polymorphonuclear leukocyte (PMNL) chemotaxis studies of 32 patients with localized juvenile periodontitis (periodontosis or LJP), 10 adult patients with a history of LJP (post-LJP), 8 patients with generalized juvenile periodontitis (GJP), and 23 adults with moderate to severe periodontitis were performed: (i) to determine the prevalence of a PMNL chemotaxis defect in a large group of LJP pati...

The appearance of this issue of PERIODONTOLOGY 2000 is a tribute to the sustained efforts of an international group of oral microbiologists, immunologists and clinical investigators. When one of us (SSS) began work in this field in 1957, Actinobacillus actinomyceterncornitans was unknown in periodontal microbiology and Porphyromonas gingiualis was not known as such, although the “black-pigmente...

Exostoses on the mandible and maxilla is a frequently observed bone growth of controversial aetiology. The aim of this study is to analyse environmental factors that may stimulate the formation of exostoses on different regions of the maxilla and mandible. Sixty-six well-preserved crania from Neolithic China were studied for the presence of buccal exostoses on the maxilla (BE) and lingual exost...

In the late 1800s, what is now known as chronic periodontitis was clinically characterized as a slowly progressive destruction of the periodontium due to the accumulation of lime deposits on the teeth (21), or calcic inflammation of the peridental membrane secondary to deposits of salivary and ⁄ or serumal calculus (13). The calcified deposits were considered to be mechanical irritants that led...

The effect of gingival curettage facilitated by sodium hypochlorite solution on the subgingiva] micro flora of 21 juvenile periodontitis lesions was evaluated. Dark-field analysis and anaerobic culturing of juvenile periodontitis lesions were made immediately prior to treatment with gingival curettage facilitated by sodium hypochlorite solution-immediately after therapy, 30 days posttherapy, an...