Some time ago Carter and Neville reported (1) that hydroxy-n-proline yields formaldehyde on oxidation with periodate. In another laboratory, this oxidation was found to produce a considerably lower yield of formaldehyde than we had obtained.’ A further study of this reaction was accordingly undertaken. Oxidation of several new samples of hydroxy-L-proline gave lower yields of formaldehyde than ...

A capsular polysaccharide produced by Aerobacter aerogenes has been purified and shown to consist of galactose, mannose, and glucuronic acid in a molar ratio of 2: 1: 1, respectively. Partial acid hydrolysis liberated an aldobiouronic acid identified as 2-0-P-D-glucuronosyl-D-mannose. Analysis of capsular polysaccharide by Smith periodate degradation further indicated that all of the galactose ...

No periodate oxidation on chitin? For the first time, direct selective alkaline of chitin led to isolation ordered domains as uniform anisotropic and zwitterionic ChNCs after simultaneous removal non-ordered domains.

We have developed a colorimetric assay for determining the degree of glycation of serum proteins that is unaffected by glycosylation residues. This was accomplished by reducing the proteins with sodium borohydride prior to periodate oxidation. Previous periodate-based methods, which offer several advantages over other glycation assays, cannot determine glycoprotein glycation because interferenc...

Dihydrostreptomycin is produced commercially by the catalytic hydrogenation of streptomycin. The reaction involves the reduction of the aldehyde group in the streptose moiety of the streptomycin molecule to the corresponding primary carbinol group as evidenced by the failure of dihydrostreptomycin to react with carbonyl reagents or with alkali to produce maltol. As there are no chemical methods...

We have treated bovine lung heparan sulfate with alkaline [3H]borohydride to end label the chains with [3H]xylitol. After subsequent periodate oxidation-alkaline elimination products were separated by gel permeation and ion exchange chromatography. The linkage region fragment expected to have 2 galactoses and 1 [‘HJxylitol residue appeared in the tetra-/trisaccharide region after gel filtration...

A study of the chemical, physicochemical, and immunological changes in bovine serum albumin, brought about by oxidation with lithium periodate, has been made. It has been shown that destruction of certain amino acids occurs, that a change in the absorption spectrum takes place, and that the electrophoretic behavior of the protein is altered. Prolonged contact of bovine albumin with lithium peri...