BACKGROUND Perinatal asphyxia is a major cause of neurologic morbidity and mortality. The purpose of this study was to investigate variations in nucleated red blood cell (NRBC) count per 100 white blood cells (WBC) and absolute NRBC/mm3 in blood associated with perinatal asphyxia and its relationship to both the severity and short term prognosis of asphyxia. METHODS A prospective (case-contro...

Perinatal asphyxia induces retinal lesions, generating ischemic proliferative retinopathy, which may result in blindness. Previously, we showed that the nitrergic system was involved in the physiopathology of perinatal asphyxia. Here we analyze the application of methylene blue, a well-known soluble guanylate cyclase inhibitor, as a therapeutic strategy to prevent retinopathy. Male rats (n = 28...

We have studied risk factors for perinatal asphyxia among babies fulfilling the inclusion criteria and compared them with matched controls. Maternal or antepartum factors included were maternal age, gestational age, hypertension, diabetes mellitus and antenatal clinic (ANC) visits less than 3. Intrapartum factors included malpresentation, mode of delivery, meconium stained amniotic fluid, Chori...

background: asphyxia is a common cause of perinatal mortality in 5-10% of all births worldwide. the present parameters for determining perinatal asphyxia, e.g. preeclampsia, cannot be considered as markers per se, and require auxiliary markers, e.g. increased number of nucleated red blood (nrbc) cells, for early diagnosis of perinatal asphyxia. objective: in this study, we evaluated the mean nr...

how to cite this article: khalessi n, khosravi n, mirjafari m, afsharkhas l. plasma ammonia levels in newborns with asphyxia. iran j child neurol. winter 2016; 10(1):42-46. abstract objective perinatal asphyxia may result in hypoxic damage in various body organs, especially in the central nervous system. it could induce cascade of biochemical events leading to the cell death and metabolic chang...

PURPOSE This study aimed to identify prognostic factors of neurological outcomes, including developmental delay, cerebral palsy and epilepsy in late-preterm and term infants with perinatal asphyxia. METHODS All late-preterm and term infants with perinatal asphyxia or hypoxic-ischemic insults who admitted the neonatal intensive care unit of Inje University Sanggye Paik Hospital between 2006 an...

objective: asphyxia  is  a  major  cause  of  acute  mortality  and  chronic  neurologic  disability  in  neonates. we sought to  define  the  predictive  values  of  serum  concentrations  of  interleukin-1β  in  newborns  with perinatal asphyxia to see if there is a relation between interleukin-1β (il-1β) levels to the short term neurological deficit.  methods: this was a prospective (case-co...

Introduction: Perinatal asphyxia, the prime cause for neonatal mortality and morbidity, results in hypoxic damage to almost all organs of the neonate, kidneys being most frequently (50%) affected. However, neonatal renal failure poses diagnostic as well as therapeutic challenge as clinical and laboratory parameters are unpredictable in this age group. Paucity of studies determining the incidenc...

BACKGROUND Poverty may moderate the effect of treatment of depression in low-income countries. AIMS To assess poverty and lack of empowerment as moderators of a cognitive-behavioural therapy (CBT)-based intervention for perinatal depression in rural Pakistan. METHOD Using secondary analysis of data from a randomised controlled trial (trial registration: ISRCTN65316374) we identified predict...

Citation: Herrera MI, Udovin LD, Toro-Urrego N, Kusnier CF, Luaces JP and Capani F (2018) Palmitoylethanolamide Ameliorates Hippocampal Damage and Behavioral Dysfunction After Perinatal Asphyxia in the Immature Rat Brain. Front. Neurosci. 12:145. doi: 10.3389/fnins.2018.00145 Palmitoylethanolamide Ameliorates Hippocampal Damage and Behavioral Dysfunction After Perinatal Asphyxia in the Immature...