1 Howard-Peebles PN, Stoddard GR. Pericentric inversions of chromosome number 9: benign or harmful. Hum Hered 1979;29:111-7. 2 Leonard C, Hazael-Massieux P, Bocquet L, Larget-Piet L, Boue J. Inversion pericentrique inv(2)(pl1ql3) dans les familles non apparent6es. Hum Genet 1975 ;48 :121-8. 3 van der Linden AGJM, Pearson PL, van de Kamp JJP. Cytological assessment of meiotic exchange in a human...

This case report presents two chromosomal inversions in one of partners from a subfertile couple. The woman was referred due to a spontaneous abortion in the 5th week of pregnancy. Cytogenetic examination showed that the proband's karyotype was normal: 46,XX,16qh+, as centromeric heterochromatin is thought to be clinically insignificant. However, the proband's partner occurred to be a carrier o...

Pericentric inversions are among the most frequent chromosomal rearrangements with a frequency of 1-2%. There is no phenotypic effect in the majority of pericentric inversion heterozygote carriers, when it is a balanced rearrangement. However, miscarriages, infertility and/or chromosomally unbalanced offspring can be observed in carriers of a pericentric inversion. This is a case of pericentric...

The nonrandom gene organization in eukaryotes plays a significant role in genome evolution and function. Chromosomal structural changes impact meiotic fitness and, in several organisms, are associated with speciation and rapid adaptation to different environments. Small sized chromosomal inversions, encompassing few genes, are pervasive in Saccharomyces "sensu stricto" species, while larger inv...

HALE, D. W. 1986. Heterosynapsis and suppression of chiasmata within heterozygous pericentric inversions of the Sitka deer mouse. Chromosoma 94: 425-432. HALE, D. W., AND I. F. GREENBAUM. 1988. Synapsis of a chromosomal pair heterozygous for a pericentric inversion and the presence of a heterochromatic short arm. Cytogenet. Cell Genet. In press. MACEY, M., AND L. K. DIXON. 1987. Chromosomal var...

The order Anguilliformes comprises 15 families, 141 genera and 791 fish species. Eight families had at least one karyotyped species, with a prevalence of 2n = 38 chromosomes and high fundamental numbers (FN). The only exception to this pattern is the family Muraenidae, in which the eight species analyzed presented 2n = 42 chromosomes. Despite of the large number of Anguilliformes species, karyo...

Genome sizes were measured and determined for the karyotypes of nine species of aphid parasitoids in the genus Aphelinus Dalman,1820. Large differences in genome size and karyotype were found between Aphelinus species, which is surprising given the similarity in their morphology and life history. Genome sizes estimated from flow cytometry were larger for species in the Aphelinus mali (Haldeman,...

BACKGROUND Pericentric inversions are structural chromosomal abnormalities resulting from two breaks, one on either side of the centromere, within the same chromosome, followed by 180 degrees rotation and reunion of the inverted segment. They can perturb spermatogenesis and lead to the production of unbalanced gametes through the formation of an inversion loop. METHODS We report here the anal...