نتایج جستجو برای: peri implant osteolysis
تعداد نتایج: 63139 فیلتر نتایج به سال:
providing an esthetic restoration in the anterior region of the mouth has been the basis of peri-implant esthetics. to achieve optimal esthetics, in implant supported restorations, various patient and tooth related factors have to be taken into consideration. peri-implant plastic surgery has been adopted to improve the soft tissue and hard tissue profi les, during and after implant placement. t...
background: receptor activator of nuclear factor kappa b ligand (rankl) is one of the key cytokines in the induction of osteoclastogenesis both in vitro and in vivo.several reports indicated the presence of srankl in gingival crevicular fluid of patients with periodontal diseases. objective: to determine the presence of rankl in peri-implant crevicular fluid samples of implants with peri-implan...
Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis
Wear particle-induced osteolysis is the leading cause of aseptic loosening, which is the most common reason for THA (total hip arthroplasty) failure and revision surgery. Although existing studies suggest that osteoblast apoptosis induced by wear debris is involved in aseptic loosening, the underlying mechanism linking wear particles to osteoblast apoptosis remains almost totally unknown. In th...
Currently, there are no medications available to treat aseptic loosening of orthopedic implants. Using osteoprotegerin fusion protein (OPG-Fc), we previously blocked instability-induced osteoclast differentiation and peri-prosthetic osteolysis. Wnt/β-catenin signaling, which regulates OPG secretion from osteoblasts, also modulates the bone tissue response to mechanical loading. We hypothesized ...
o bjective : increased levels of oxidative stress markers in periodontitis have been reported by recent studies. malondialdehyde (mda) and superoxide dismutase (sod) are both in- creased during oxidative stress. the aim of this study was to detect and measure the level of oxidative stress markers in peri-implant crevicular fluid (picf). their correlation with peri-implant clinical parameters wa...
Patients with osteoporosis and joint disabilities represent a constant growing and challenging population to be treated in the musculoskeletal clinical field. Especially in the case of total hip arthroplasty, new solutions should be developed to compensate for the double negative factors, peri-implant osteolysis, and osteoporotic bone loss, affecting the quality of implant outcome. The goal of ...
BACKGROUND Emerging longitudinal data appear to demonstrate an alarming trend towards an increasing prevalence of osteolysis-induced mechanical failure, following total knee replacement (TKR). Even with high-quality multi-plane X-rays, accurate pre-surgical evaluation of osteolytic lesions is often difficult. This is likely to have an impact on surgical management and provides reasonable indica...
Wear debris-induced osteolysis in periprosthetic tissue with aseptic loosening is a serious problem after total joint arthroplasty. Matrix metalloproteinase-9 (MMP-9) is expressed in osteoclast cells that surround loosening peri-implant tissue, but the molecular mechanism of MMP-9 action in wear debris-induced osteolysis remains ambiguous. We used a murine osteolysis model to examine the hypoth...
BACKGROUND Wear particle-induced peri-implant loosening is the most common complication affecting long-term outcomes in patients who undergo total joint arthroplasty. Wear particles and by-products from joint replacements may cause chronic local inflammation and foreign body reactions, which can in turn lead to osteolysis. Thus, inhibiting the formation and activity of osteoclasts may improve t...
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