BACKGROUND The aim of this study was to evaluate factors influencing the 99th percentile for cardiac troponin I (cTnI) when this cutoff value is established on a highly sensitive assay, and to compare the value of this cutoff to that of lower cutoffs in the prognostic assessment of patients with coronary artery disease. METHODS We used the recently refined Access AccuTnI assay (Beckman-Coulte...

Abstract Objective This study involved the preparation of high score multivariate base rates for Spanish-language NIH Toolbox Cognition Battery (NIHTB-CB) to inform neuropsychological practice with high-functioning Spanish-speaking patients. Method Participants included 250 healthy adults from NIHTB-CB normative sample (M = 38.8 ± 13.7 years-old; 72.0% women; 100% Latinx) who completed full bat...

BACKGROUND Data regarding the familial aggregation of left ventricular (LV) geometry and its relations to parental heart failure (HF) are limited. METHODS AND RESULTS We evaluated concordance of LV geometry within 1093 nuclear families in 5758 participants of the original (parents) (n=2351) and offspring (n=3407) cohorts of the Framingham Heart Study undergoing routine echocardiography in mid...

BACKGROUND The test characteristics of head circumference (HC) measurement percentile criteria for the identification of previously undetected pathology associated with head enlargement in primary care are unknown. METHODS Electronic patient records were reviewed to identify children age 3 days to 3 years with new diagnoses of intracranial expansive conditions (IEC) and metabolic and genetic ...

Low flow events (a.k.a. streamflow drought) are described as episodes where stream flows lower or equal to a specified minimum threshold level. This is usually predefined at the methodological stage of study and generally applied chosen percentile, determined from duration curve (FDC). Unfortunately, many available methods for choosing both percentile FDCs result in large range potential thresh...

Using empirical data I demonstrate that the result of performance evaluations by percentiles can be drastically influenced by the proper choice of the journal in which a manuscript is published. 1. Introduction In order to evaluate the impact of publications in terms of citation counts recently percentile-based bibliometric indicators have gained more and more attention (Bornmann, Leydesdorff, ...

We determined brain to liver weight ratio (BLWR) thresholds for fetal growth restriction (FGR) using autopsy information on 395 perinatal deaths comprising stillborn babies who died during labour and neonatal deaths. FGR was defined using two methods: (1) birth weight for gestational age (WGA) less than the 10th percentile; and (2) WGA less than the 10th percentile or discordant birth weight/le...