Introduction: Growth and proliferation of the remaining microorganisms within the root canals may destroy the surrounding tissue of the root and leads to periapical lesion. Consequently, the complete elimination of microorganisms from the root canal is a n important goal of endodontic therapy. Endodontic sealers do not provide complete seal in root canal system, and micro spaces have always rem...

Bacterial penetration shortly after inoculation has not been reported extensively. Four strains of bacteria, Salmonella typhimurium (ST), Escherichia coli (EC), Pseudomonas earuginosa (PE) and Stapylococcus aureus (SA), in chicken egg components of Bovan brown were analyzed by serial dilution and scanning electron microscopy. After exposing the fresh eggs to the bacterial strains at concentrati...

Gram-negative bacteria are notoriously resistant to antibiotics, but the extent of the resistance varies broadly between species. We report that in significant human pathogens Acinetobacter baumannii, Pseudomonas aeruginosa, and Burkholderia spp., the differences in antibiotic resistance are largely defined by their penetration into the cell. For all tested antibiotics, the intracellular penetr...

Rifampin penetrated biofilms formed by Staphylococcus epidermidis but failed to effectively kill the bacteria. Penetration was demonstrated by a simple diffusion cell bioassay and by transmission electron microscopic observation of antibiotic-affected cells at the distal edge of the biofilm.

As one of the emerging soil improvement techniques, microbial induced calcite precipitation (MICP) can bond soil grains together and improve the engineering properties of soil [1]. bacteria produces urease enzyme can catalyze urea to carbonate and result in calcite precipitation in elevated pH environment. The forms of calcite precipitation around the bacteria limit the availability of oxygen a...

BACKGROUND To identify changes in cefoperazone/sulbactam penetration into cerebrospinal fluid (CSF) after craniotomy and to investigate preliminarily whether cefoperazone/sulbactam CSF concentration can reach therapeutic level when administered intravenously after neurosurgical operation. METHODS Neurosurgical patients with an indwelling ventricular drainage pipe who received prophylactic cef...