نتایج جستجو برای: peg 200
تعداد نتایج: 154699 فیلتر نتایج به سال:
Abstract The aim was to produce PEG-coated nanoparticles (NP-PEG), with mucus-permeating properties, for oral drug delivery purposes by using simple procedures and regulatory-approved compounds in order facilitate a potential clinical development. For this purpose, zein were prepared desolvation and, then, coated incubation PEG 35,000. resulting nanocarriers displayed mean size of about 200 nm ...
Splenectomized mice treated for 7 days with pegylated recombinant rat stem cell factor (rrSCF-PEG) showed a dosedependent increase in peripheral blood progenitor cells (PBPC) that have enhanced in vivo repopulating potential. A dose of rrSCF-PEG at 25 pg/kg/d for 7 days produced no significant increase in PBPC. However, when this dose of rrSCF-PEG was combined with an optimal dose of recombinan...
Ruthenium oxide nano-catalysts supported on mesoporous γ-Al2O3 have been prepared by co-precipitation method and tested for CO oxidation. The effect of polyethylene glycol (PEG) on the properties of the catalyst was studied. Addition of the PEG surfactant acted as a stabilizer and induced a change in the morphology of ruthenium oxide from spherical nanoparticles to one-dimensional nanorods. Tot...
BACKGROUND Asunaprevir is a selective NS3 protease inhibitor with in vitro activity against HCV genotypes 1 and 4. METHODS In this Phase IIa double-blind study, treatment-naive HCV genotype-1-infected patients in the United States and France were randomly assigned 1:1:1:1 to placebo or asunaprevir 200 mg twice daily, 600 mg twice daily or 600 mg once daily in combination with pegylated interf...
IMPORTANCE Patients with oropharyngeal squamous cell carcinoma undergoing chemoradiotherapy may require percutaneous endoscopic gastrostomy (PEG) tube placement because of dehydration or significant weight loss. OBJECTIVES To determine the need for the reactive placement of a PEG tube during chemoradiotherapy for oropharyngeal cancer and to identify patient or tumor factors associated with re...
The effect of polyethylene glycol (PEG) on intake and digestibility in Sarda goats either fed in metabolic crates or browsing a Mediterranean scrubland, featured by tannin-rich species, was studied. In metabolic cages (Experiment 1) nine dry goats were fed ad libitum with foliage of lentisk (Pistacia lentiscus L.) supplemented with 200 g per day of a concentrate and either 0, 25 or 50 g per day...
G-quadruplex topologies of telomeric repeat sequences from vertebrates were investigated in the presence of molecular crowding (MC) mimetics, namely polyethylene glycol 200 (PEG), Ficoll 70 as well as Xenopus laevis egg extract by CD and NMR spectroscopy and native PAGE. Here, we show that the conformational behavior of the telomeric repeats in X. laevis egg extract or in Ficoll is notably diff...
Background and Aims: Hepatitis B surface antigen (HBsAg) loss is seldom achieved with nucleos(t)ide analog (NA) therapy in chronic hepatitis B patients but may be enhanced by switching to finite pegylated-interferon (Peg-IFN) alfa-2a. We assessed HBsAg loss with 48- and 96-week Peg-IFN alfa-2a in chronic hepatitis B patients with partial response to a previous NA. Methods: Hepatitis B e antigen...
A striking contrast in the thermal conductivities of polyethylene glycol (PEG)/diatomite form-stable phase change composite (fs-PCC) with single-walled carbon nanotubes (SWCNs) as nano-additive has been reported in our present study. Compared to the pure PEG, the thermal conductivity of the prepared fs-PCC has increased from 0.24 W/mK to 0.87 W/Mk with a small SWCNs loading of 2 wt%. SWCNs are ...
BACKGROUND Chronic hepatitis C virus (HCV) infection is associated with liver dysfunction and hepatocellular carcinoma. In patients with normal kidney function, treatment with pegylated interferon (PEG-IFN) and ribavirin (RBV) frequently leads to eradication of HCV. Treatment in dialysis patients has long been controversial and until recently, the use of RBV was considered to be contra-indicate...
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