The worldwide epidemic of childhood obesity in the last decades is responsible for the occurrence in pediatrics of disorders once mainly found in adults, such as the metabolic syndrome. A key factor in the pathogenesis of metabolic syndrome is insulin resistance, a phenomenon occurring mainly in obese subjects with a general resistance to the insulin effect only on carbohydrates metabolism. Giv...

The epidemic spread of obesity in the last twenty years has led in pediatric setting to the appearance of diseases previously considered a prerogative of adulthood, such as metabolic syndrome (MetS). The Metabolic Syndrome is characterized by a cluster of cardiometabolic abnormalities, including visceral obesity, dyslipidemia, hypertension and diabetes mellitus type 2, that directly increase th...

BACKGROUND Obesity is a global epidemic and its morbidities such as metabolic syndrome, insulin resistance, and fatty liver leads to a spectrum of psycho-social and medical consequences. OBJECTIVES The objective of this study was to investigate the prevalence of fatty liver in obese Iranian children and its' association with metabolic syndrome and insulin resistance. PATIENTS AND METHODS 10...

Prevalence of metabolic syndrome in children and adolescents is increasing, in parallel with the increasing trends in obesity rates. Varying definitions of this syndrome have hindered the development of a consensus for the diagnostic criteria in the pediatric population. While pathogenesis of metabolic syndrome is not completely understood, insulin resistance and subsequent inflammation are tho...

Background/Objectives: Childhood obesity represents the most relevant nutritional disorder in our environment. This study examines the prevalence of metabolic syndrome in an obese pediatric population and its relation to serum Leptin concentrations. Subjects/Methods: A cross-sectional clinical and metabolic study was accomplished in a group of 106 obese children (47 males and 59 females). Patie...

background:the current study aimed at evaluating the association between thyroid-stimulating hormone (tsh) level in upper normal limits with metabolic syndrome, modifiable risk factor for cardiovascular disease, and its components according to adult treatment panel iii of national cholesterol education program. methods: the current cross sectional study recruited 82 patients with euthyroid over...

objectives the aim of this study was to evaluate the effect of cranberry extract on some components of metabolic syndrome. patients and methods in a randomized, double-blind placebo-controlled clinical trial, 48 obese and overweight females diagnosed with ms were assigned into two groups to receive cranberry supplement or placebo for an eight-week period. serum glucose, lipoproteins, inflammato...

conclusions there was a significant association between pms scores and the prevalence of metabolic syndrome. further studies are needed to confirm and validate the relationships between lipid profile abnormalities and metabolic disorders with pms. objectives this study was designed to investigate the association of hormonal and metabolic factors with pms among iranian women of reproductive age....