BACKGROUND The prevalence of pedal edema (PE) and its associations with abnormal cardiac structure/function, natriuretic peptides, and incident heart failure (HF) is unknown, especially in community-dwelling adults without a history of cardiovascular disease. METHODS AND RESULTS Out of 5004 MESA (Multiethnic Study of Atherosclerosis) participants who had cardiac magnetic resonance imaging, 41...

OBJECTIVE Pre-eclampsia (PE) is associated with an increased risk of cardiovascular disease later in life. In cases with PE there is a substantial increase in levels of the antiangiogenic factor soluble fms-like tyrosine kinase-1 (sFlt-1) and decreased levels of the proangiogenic factor placental growth factor (PlGF). Elevated levels of sFlt-1 are also found in individuals with cardiovascular d...

OBJECTIVE To evaluate the performance of angiogenic factors, maternal risks and uterine artery Doppler (UAD) in the prediction of pre-eclampsia (PE) and fetal growth restriction (FGR) in a high-risk Ecuadorian population. METHODS Patients with singleton pregnancies (n = 346) were investigated at two clinical visits (18-25 weeks and 28-32 weeks). Mean uterine artery (UA), pulsatility index (PI...

OBJECTIVE Chronic kidney disease (CKD) and preeclampsia (PE) may both present with hypertension and proteinuria in pregnancy. Our objective is to test the possibility of distinguishing CKD from PE by means of uteroplacental flows and maternal circulating sFlt-1/PlGF ratio. DESIGN Prospective analysis. POPULATION Seventy-six patients (35 CKD, 24 PE, and 17 other hypertensive disorders), with...

Background: Cytomegalovirus (CMV) infection is one of the most common infectious diseases in pregnant women in terms of global impact and is related with many adverse health consequences during pregnancy. For the first time, we performed a systematic review and meta-analysis study to evaluate the possible association between CMV infection and preeclampsia (PE). Methods: A comprehensive literat...

This paper reports preliminary experimental evaluation of a Processing Elements Stealing (PE-S) technique which was targeted as efficient and scalable load balancing technique for dynamically structured multiprocessor systems. The multiprocessor system is imagined as a dynamic cluster based multiprocessor. Each cluster of the multiprocessor system is a node in symmetric multiprocessor architect...

BACKGROUND Current guidelines recommend that transthoracic echocardiography (TTE) should be performed for acute risk stratification following acute pulmonary embolism (PE), but it is unclear whether the initial TTE can predict long-term outcome beyond six months. We sought to assess the potential of the initial right atrial (RA) to left atrial (LA) area ratio (RA/LA ratio) on TTE to predict lon...

INTRODUCTION Contrast-enhanced multidetector computed tomography (MDCT) is useful for the diagnosis of pulmonary embolism (PE). However, current guidelines do not support its use for risk assessment in acute PE patients. OBJECTIVES We compared the prognostic impact of MDCT-derived indices regarding medium-term mortality in a population of intermediate- to high-risk PE patients, mostly treated...

background: pulmonary embolism (pe) is the most life-threatening form of venous thrombosis which causes the majority of mortalities in this category. obstructive sleep apnea (osa) has been indicated as one of the risk factors for thromboembolism because of hemostatic alterations. the present study was designed to seek for the relationship between osa and 30-day mortality of patients with pe. ma...

OBJECTIVE We sought to investigate the impact of emotional and surgical stress applied in two hormonally different estrous-cycle phases as well as the hypothalamic dopaminergic involvement on the rapid compensatory adrenal growth (CAG) and the individual adrenal growth (IAG) in rats. DESIGN After surgery for left and sham adrenalectomy (Adx) carried out on either diestrus-2 (DE-2) or proestru...