Centrosomes are major microtubule-nucleating organelles that facilitate chromosome segregation and cell division in metazoans. Centrosomes comprise centrioles that organize a micron-scale mass of protein called pericentriolar material (PCM) from which microtubules nucleate. During each cell cycle, PCM accumulates around centrioles through phosphorylation-mediated assembly of PCM scaffold protei...

This paper presents results of research on network-based positioning for UMTS (universal mobile telecommunication system). Two new applicable network-based cellular location methods are proposed and assessed by field measurements and simulations. The obtained results indicate that estimation of the position at a sufficient accuracy for most of the location-based services does not have to involv...

Paracoccidioidomycosis (PCM) is an infection caused by the dimorphic fungus Paracoccidioides brasiliensis, which has a predilection for hot and humid places; thus, this disease particularly high incidence in Brazil. Children, adolescents, adults can be affected acute/subacute or chronic PCM. To describe clinical-pathological characteristics treatment of case PCM oral lesion. The examination 57-...

Phase Change Memory (PCM) has better scalability and smaller cell size comparing to DRAM. However, further scaling PCM cell in deep sub-micron regime results in significant thermal based write disturbance. Naively allocating large inter-cell space increases cell size from ideal 4F 2 to 12F 2. While a recent work mitigates write disturbance along word-lines through disturbance resilient data enc...

Phase change memory (PCM) is a byte-addressable type of non-volatile memory. Compared to other volatile and non-volatile memories, PCM is two to four times denser than dynamic random access memory (DRAM). It has better read latency than NAND flash memory. Even though the write endurance of PCM is 10 times better than NAND flash memory, it is still limited to times per PCM cell. When researchers...

The aim of this study was to explore the incidence and risk factors for posterior cage migration (PCM) following decompression and instrumented fusion for degenerative lumbar disorders, and hope to provide references in decision making and surgical planning for spine surgeons.By retrieving the medical records from January 2011 to December 2015, 286 patients were retrospectively reviewed. Accord...

During cell division, cells form the microtubule-based mitotic spindle, a highly specialized and dynamic structure that mediates proper chromosome transmission to daughter cells. Cancer cells can show perturbed mitotic spindles and an approach in cancer treatment has been to trigger cell killing by targeting microtubule dynamics or spindle assembly. To identify and characterize proteins necessa...

Protein carboxy-O-methyltransferase (PCM) activity was determined in subcellular fractions prepared from C-1300 neuroblastoma tumors following transplantation and growth in male A/J mice. Fractions were obtained by differential centrifugation, and PCM activity was determined in all fractions in the presence (+gel) and absence (-gel) of an exogenous substrate, gelatin. Sixty % of the PCM activit...

BACKGROUND Paracetamol is recommended as first line agent for pain management in osteoarthritis (OA) by various guidelines. The main problem associated with management of osteoarthritis is long term patient compliance to paracetamol due to its frequent dosing. OBJECTIVE To evaluate the efficacy and safety of Paracetamol 650 mg dual release tablet twice daily (PCM 650 dual release) compared to...