Focal therapy for prostate cancer has been proposed as an alternative treatment to whole gland therapy, offering the opportunity for tumor dose escalation and/or reduced toxicity. Brachytherapy, either low-dose-rate or high-dose-rate, provides an ideal approach, offering both precision in dose delivery and opportunity for a highly conformal, non-uniform dose distribution. Whilst multiple consen...

background among all pediatric cancers acute lymphoblastic leukemia (all) is highly prevalent, butthe overall cost of all management is not well-known, there is a need to assess the berlin-frankfurt-munster (bfm) protocol commonly used in all management in iran. so, the aim of this study was to estimate direct and indirect costs of all treatment among children based on the all-bfm protocol from...

background: myocardial infarction (mi) occurs due to heart muscle death that costs like human life, which is higher than the treatment costs. this study aimed to present an mi prediction model using classification data mining methods, which consider the imbalance nature of the problem. methods: we enrolled 455 healthy and 295 myocardial infarction cases of visitors to shahid madani specialized ...

patient's refusal of treatment is the rational consequence of informed consent and is considered among the patient's rights but can lead to patient harm or harm to others, or damage to the health care system. major ethical challenges in the field of treatment refusal arise from capacitated patients. this paper mainly examines theoretical issues related to this group by reviewing books...

BACKGROUND Treatment-emergent comorbid events (TECs) are common In patients initiating treatment with pegylated interferon alpha (PEG-IFN-alfa) and ribavirin for chronic hepatitis C virus (HCV) infection. The purpose of this study was to estimate the incidence and incremental cost of these events. METHODS In a retrospective cohort analysis of healthcare claims, we studied patients with HCV wh...

BACKGROUND: Various options are available for the local control of cancer in the breast -- mastectomy, conservation therapy, and mastectomy with reconstruction. METHODS: To evaluate the benefits and drawbacks of the available management options, the authors combine their extensive experience with a review of the literature on outcomes from these approaches. RESULTS: Conservation therapy provide...

aim : this study compared pr and nb in predicting hcv patient costs. the objective of this study was to predict the direct cost of the hcv patient in iran. background : hepatitis c virus (hcv) is a common and expensive infectious disease in iran. cost associated with hcv and its complications has not been well characterized. analysis of cost data is important in providing consistent information...

BACKGROUND The total cost of treating otitis media in the United States alone is estimated at > 3.5 billion dollars annually. Therefore treatment approaches that reduce the cost of managing otitis media can have a large impact on overall health care costs. METHODS In this study cost effectiveness factors of various antimicrobial agents, such as adverse events and overall patient acceptance, w...