The problem of designing new peptides that possess specific properties, such as bactericidal activity, is of wide interest. Recently, attention has focused on the use of Computer-Aided Molecular Design techniques in parallel with more traditional 'synthesise and test' methods. These techniques may typically use Genetic Algorithms to optimise molecules based on Neural Network models that predict...

A young woman had a pulmonary arteriovenous fistula localized to the right lower lobe. The presence of a patent foramen ovale (atrial septal defect) detected preoperatively allowed for a unique investigation of this case. Her successful surgical management is outlined and the literature is reviewed.

this paper using endogenous growth models based on research and development, has investigated two economic relations in three groups of countries included developed countries, developing countries and a mixed group of both mentioned ones. at first, the effects of r&d; activities on patent growth have examined and then the relation between volume of patent and growth rate in these groups has sur...

This case report was an attempt to present the importance of diagnostic echocardiography and closure of a patent foramen ovale in carcinoid heart disease. Herein, we present a case of a 48-year-old woman with a carcinoid metastasis presenting with tricuspid regurgitation, pulmonic stenosis, patent foramen ovale, and borderline left ventricular ejection fraction on an echocardiogram. Surgical in...

persistent patent urachus with other accompanying anomalies like urethral obstruction and uroperitoniumquickly deteriorates animal conditions which necessitate prompt surgical intervention and animal salvage. a10-day-old calf was referred to clinic with mildly distended abdomen, history of umbilical dribbling and nosigns of normal urination since birth. on clinical laboratory results and ancill...