Epicutaneous patch testing is the gold standard method for the diagnosis of allergic contact dermatitis. Despite this knowledge, many clinical dermatologists do not offer patch testing in their offices or offer testing with only a limited number of allergens. Introduced in 1995, the Thin-Layer Rapid Use Epicutaneous Test originally contained 23 allergens and one control. In 2007, five additiona...

Dermatologists use the terms “eczema” and “dermatitis” interchangeably to describe a varied pattern of inflammation which, when acute, is characterised by erythema and vesiculation, and, when chronic, by dryness, lichenification, and fissuring (fig 1). Contact dermatitis is the consequence of a pathological response to one or more external agents that may act either as irritants, where allergic...

Software patches are often poorly tested, with many of them containing faults that affect the correct operation of the software. In this paper, we propose an automatic technique based on symbolic execution, that aims to increase the quality of patches by providing developers with an automated mechanism for generating a set of comprehensive test cases covering all or most of the statements in a ...

Skin testing with the suspected drugs may be helpful in determining the cause of a cutaneous adverse reaction (CADR). Tetrazepam (T) is a muscle relaxant of the benzodiazepine group frequently used in rheumatology in association with anti-inflammatory drugs (AIDs). We propose to determine the usefulness of patch testing in this context. Patients and methods A retrospective study was conducted i...

Allergic contact dermatitis (ACD) may complicate the clinical course of atopic dermatitis (AD), and patch testing remains the criterion standard for diagnosing ACD. To date, there have been no guidelines or consensus recommendations on when and how to patch test individuals with AD. Failure to patch test when appropriate may result in overlooking an important and potentially curable complicatin...

Adverse food reaction (AFR) is a common differential diagnosis for pruritic dogs. The only way to diagnose AFR is an elimination diet of 6-8 weeks with a protein and a carbohydrate source not previously fed. In humans, patch testing has been shown to be a useful tool to diagnose food allergies. In veterinary medicine, serum food allergen-specific antibody testing is widely offered to identify s...

OBJECTIVE To determine the effect of patch testing on surgical decision making and outcomes in patients evaluated for suspected metal hypersensitivity related to implants in bones or joints. DESIGN Medical chart review. SETTING Tertiary care academic medical center. PARTICIPANTS All patients who had patch testing for allergic contact dermatitis related to orthopedic implants. INTERVENTI...

BACKGROUND Burning mouth syndrome (BMS) is a burning or sore mouth in the absence of changes in the oral mucosa. It is often difficult to diagnose and treat. Numerous theories of the etiology have been suggested, including contact allergy. OBJECTIVE To determine the clinical utility of patch testing in patients with BMS. METHODS We retrospectively reviewed the charts of patients diagnosed w...