Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

the dynamic response of a transversely isotropic, linearly elastic layer bonded to the surface of a half-space of a different transversely isotropic material under arbitrary shape surface loads is considered. with the help of displacements and stresses green’s functions, an analytical formulation is presented for the determination of the displacements and stresses at any point in both surface l...

abstract competition is a phenomenon that influences the size, structure and stability of insect communities, particularly on solitary endoparasitoids species. although, competition normally incurs costs, it might be adaptive for the surviving individual. to determine which factors affect the patch use strategy of foragers under competition, the effect of previous experience with hosts already-...

An equivalent circuit model for predicting the frequency response of a square ring slot frequency selective surface (SRS-FSS) for normal incidence is described. The proposed FSS consists of an array of square patches centered within a wire grid. The presented circuit model is formed by the impedance of the wire grid that is parallel with the impedance of the patch array, also the mutual couplin...

A modified circular patch antenna design has been proposed in this paper, the bandwidth of this antenna is optimized using the genetic algorithm (GA) based on fuzzy decision-making. This design is simulated with HP HFSS Program that based on finite element method. This method is employed for analysis at the frequency band of 1.4 GHz- 2.6 GHz. It gives good impedance bandwidth of the order o...

Contraceptive patches have become a frequently used contraceptive method. We present a mathematical model that describes the serum concentration profiles of Norelgestromin (NGMN) and Ethinylestradiol (EE) released from the contraceptive patch Ortho Evra®. We propose a simple one-compartment model based on pharmacokinetics data reported in previous studies. The model assumes a time-dependent rel...

Contraceptive patches have become a frequently used contraceptive method. We present a mathematical model that describes the serum concentration profiles of Norelgestromin (NGMN) and Ethinylestradiol (EE) released from the contraceptive patch Ortho Evra®. We propose a simple one-compartment model based on pharmacokinetics data reported in previous studies. The model assumes a time-dependent rel...

contact dermatitis is frequent skin pathology and eyelids are one of the more frequent locations of this pathology. the objective of the present work was to study the population distribution of periocular dermatitis, determine the allergens which most frequently indicate positive in patch tests and in provocative use tests, and analyse the clinical relevance of the positive tests. patients with...

contraceptive patches have become a frequently used contraceptive method. we present a mathematical model that describes the serum concentration profiles of norelgestromin (ngmn) and ethinylestradiol (ee) released from the contraceptive patch ortho evra®. we propose a simple one-compartment model based on pharmacokinetics data reported in previous studies. the model assumes a time-dependent rel...

Background: Various environmental factors can induce or exaggerate hand eczema. Objective: Evaluation of patch test results in hand eczema patients. Patients and Methods: In this descriptive study 100 patients with hand eczema referred to Loghman Hakim and Booali Hospital in Tehran underwent patch testing with 23 allergens obtained from Hermal company. Results: 240 positive reactions observed i...