This paper reports a new low-cost passive microfluidic mixer design, based on a replication of identical mixing units composed of microchannels with variable curvature (clothoid) geometry. The micromixer presents a compact and modular architecture that can be easily fabricated using a simple and reliable fabrication process. The particular clothoid-based geometry enhances the mixing by inducing...

A micromixer with unbalanced three-split rhombic sub-channels was proposed, and analyses of the mixing and flow characteristics of this micromixer were performed in this work. Three-dimensional Navier-Stokes equations in combination with an advection-diffusion model with two working fluids (water and ethanol) were solved for the analysis. The mixing index and pressure drop were evaluated and co...

We assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipe...

This review reports the progress on the recent development of micromixers. The review first presents the different micromixer types and designs. Micromixers in this review are categorized as passive micromixers and active micromixers. Due to the simple fabrication technology and the easy implementation in a complex microfluidic system, passive micromixers will be the focus of this review. Next,...

(1) Background: Microfluidic chips have found extensive applications in multiple fields due to their excellent analytical performance. As an important platform for micro-mixing, the performance of micromixers has a significant impact on analysis accuracy and rate. However, existing with high mixing efficiency are accompanied by pressure drop, which is not conducive integration micro-reaction sy...

When working with cells, the first step is often to lyse them in order to get the cellular content before analysis. Some bacteria, especially gram-positive, may be difficult to lyse with conventional lysis buffer. If the cells are not properly lysed, the quality of the analysis results might suffer. In this paper, a planar micromixer design based on a splitting and recombination (SAR) concept w...

numerical investigation of 3d electrokinetic mixing through micromixer has performed both qualitatively and quantitatively. in order to reduce numerical expenses of 3d flows, we implement the helmholtz-smoluchowski method for the numerical modeling of electroosmotic flows. according to the previous study of electrokinetic mixing inside the heterogeneous microchannels, existence of the vortexes ...