Fetal parvovirus B19 infection causes anemia, hydrops, and pregnancy loss but is generally not considered teratogenic. Nevertheless, disturbances of neuronal migration have been described with congenital parvovirus infection. We evaluated a term infant with congenital parvovirus disease and polymicrogyria. We compared this case with four other reports of central nervous system disease after bir...

background and objectives: infection with parvovirus may induce spontaneous abortion, non-immune hydrops fetalis, and intrauterine death in full term infants. the aim of this study was to determine the frequency of parvovirus b19 in paraffin-embedded formalin fixed placental tissues in lost fetuses by pcr method and comparison with its frequency in healthy full term neonates as controls. mater...

Using random PCR in combination with next-generation sequencing, a novel parvovirus was detected in the brain of a young harbor seal (Phoca vitulina) with chronic non-suppurative meningo-encephalitis that was rehabilitated at the Seal Rehabilitation and Research Centre (SRRC) in the Netherlands. In addition, two novel viruses belonging to the family Anelloviridae were detected in the lungs of t...

In India, Canine Parvovirus Infection is an endemic viral disease-causing severe gastroenteritis and significant numbers of deaths in puppies, even vaccinated populations. A retrospective study was conducted between June, 2021 2022 around Pantnagar, Uttarakhand, which cases gastro-enteritis were screened for canine parvovirus infection. total 258 out 627 presented found to be positive based on ...

BACKGROUND Psychological stress is thought to be an important factor in the pathogenesis of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). Therefore, we sought to examine this relationship in the context of parvovirus B19 infection. METHODS Thirty-nine patients with laboratory-documented acute parvovirus B19 infection were asked to complete questionnaires on negative life events...

Lung tissue from 13 cases of unexplained non-immunological hydrops fetalis was examined by in situ hybridisation to detect parvovirus. Four specimens contained parvovirus DNA in cells in the blood vessel lumina and alveoli. Twenty six control cases were negative for parvovirus DNA. As there was no known epidemic of parvovirus infection during the study period, this suggests that parvovirus is a...

Simian parvovirus is a recently discovered parvovirus that was first isolated from cynomolgus monkeys. It is similar to human B19 parvovirus in terms of virus genome, tropism for erythroid cells, and characteristic pathology in natural infections. Cynomolgus monkeys were infected with simian parvovirus to investigate their potential usefulness as an animal model of human B19 parvovirus. Six adu...

Since the discovery of parvovirus B19 by Ivonne Cossart 25 years ago, the knowledge of infection due to this virus has evolved from self-limiting erythema in-fectiosum in immunocompetent children to lethal cytopenia in immunocompro-mised patients. Now, it is possible to prevent these life-threatening parvovirus B19–mediated diseases [2, 3]. In this issue of Clinical Infectious Diseases , Lindbl...

Two Japanese outbreaks of erythema infectiosum were investigated for evidence of human parvovirus infection by a solid phase antibody capture radioimmunoassay based on a monoclonal antibody to human parvovirus. Specific IgM and high concentrations of specific IgG were detected in 37 sera from 27 children with erythema infectiosum. No anti human parvovirus IgM was detected in a remaining case of...

The nucleic acid of chicken parvovirus-like particles showed sensitivity to DNase and S1 nuclease treatment and resistance to digestion with RNase. Viral DNA readily served as a template for self-primed conversion in vitro into a double-stranded form of about 5200 base pairs. There was no evidence for encapsidation of strands of opposite polarities. These findings confirm the taxonomic classifi...