PURPOSE To develop a highly sensitive method for in vivo quantitation of intravitreal peroxides by vitreous fluorophotometry with 2',7'-dichlorofluorescin (DCFH), a hydrogen peroxide (H2O2)-sensitive fluorescent dye, and to measure peroxides in the vitreous humor after panretinal laser photocoagulation (PRP). METHODS In the presence of H2O2 and lipid hydroperoxides, nonfluorescent DCFH was ox...

It was previously reported that injection of whole blood or hemoglobin into the rabbit vitreous is followed by two periods of immigration of phagocytic cells. The first period occurs within the first few days, and the second at round 3 weeks after experimental injury. In this report, invasive cells from these two periods after intravitreal hemoglobin injection were tested for their ability to r...

purpose: to describe the association between optic disc traction and non-arteritic anterior ischemic optic neuropathy (naion). methods: eighty three eyes of 83 patients with naion were evaluated by optical coherence tomography (oct) for detecting vitreous adhesion to the optic nerve head with separation from adjacent retina (partial posterior vitreous detachment). those who were negative for su...

A case is presented of a very rare type of Usher's syndrome detected in a 30-year-old woman in her 28th week of pregnancy. She reported left eye visual impairment with a one-month history. She underwent standard ophthalmologic examination with additional procedures scheduled after childbirth, including fluorescein angiography, visual field (Goldman and Octopus) and electroretinography. Fundus e...

Human being gets about 90% of the information via visual sense[1,2]. Therefore, it is generally thought that the sight greatly influences the QOL (quality of life) of people. It is a vitreous body to take an important role to obtain visual information[3]. The vitreous body, which holds about 80% of the volume of the eyeball, is located between the crystalline lens, a ciliary body and the retina...

With the dissemination of optical coherence tomography over the past two decades, the role of persistent vitreomacular adhesion (VMA) in the development of numerous macular pathologies - including idiopathic macular hole, vitreomacular traction syndrome, cystoid and diabetic macular edema, neovascularization in diabetic retinopathy and retinal vein occlusion, exudative age-related macular degen...

Hyaluronic acid is a mucopolysaccharide. The chemical structure and properties of this group have been extensively studied (Brimacombe and Webber 1964; Schubert and Hamerman 1968; Mathews 1975; Laurent 1987). Hyaluronic acid is present in the connective tissue. It was discovered by Meyer and Palmer (1934) in the vitreous body tissue where its concentration ranges from 140 to 338 mg/dm (Laurent ...

Author’s address: Prof. Dr. A. Hagedoorn, Oogheelkundige Kliniek van het Academisch Ziekenhuis der Vrije Universiteit, De Boelelaan 1117, Amsterdam (The Netherlands) Firstly, I should like to show you a preparation of the retina and eye of a patient with a horseshoe tear of the retina followed by a recent detachment of the retina. Unfortunately, the patient died shortly after a scleral resectio...

A series of 54 non-myopic aphakic eyes with no signs of posterior vitreous detachment and 63 non-myopic aphakic eyes with various stages of posterior vitreous detachment was followed-up for a period of 6 months to 6 years. Over half of the eyes with no vitreous detachment when first examined developed various stages of posterior vitreous detachment during the follow-up period; in 10 eyes this w...