Benign familial neonatal convulsions 20q13 KCNQ2 (1–3) 8q24 KCNQ3 (4,5) Childhood absence epilepsy 8q24 ? (6,7) AD Juvenile myoclonic epilepsy 6p21 ? (8–14) 5q14 ? (15,16) 5q34 GABRA1 (17) Adolescent-onset idiopathic generalized epilepsies 8p12 ? (14,18) 18q12 ? (14) 5p ? (14) Idiopathic generalized epilepsy 3q26 ? (19) 14q23 ? (19) 2q36 ? (19) Benign familial infantile convulsions 19q ? (20) 1...

We report on a family having partial epilepsy with simple inheritance. The affected members commonly have aphasic episodes with secondary generalization; onset occurred either in adolescence or adulthood. Patients' response to medication has varied greatly. No neurological defects or decline in intelligence were found. The case represents another variety of rare familial partial epilepsy with n...

Examining the spontaneous activity to understand the neural mechanism of brain disorder is a focus in recent resting-state fMRI. In the current study, to investigate the alteration of brain functional connectivity in partial epilepsy in a systematical way, two levels of analyses (functional connectivity analysis within resting state networks (RSNs) and functional network connectivity (FNC) anal...

INTRODUCTION Vagus nerve stimulation (VNS) is an effective alternative treatment for patients with partial refractory epilepsy. Nevertheless, information regarding VNS in children is still limited. MATERIALS AND METHODS The clinical efficacy, safety and neuropsychological effects of VNS in 34 children (mean age 11.5 years) with drug-resistant epilepsy were studied. Mean follow-up was 30.8 mon...

1. Seizure semiology of these patients was not included in the study. Semiology may be helpful to further classify these patients as benign partial epilepsy in infancy with complex partial seizures versus benign partial epilepsy in infancy with secondary generalized seizures (SGS). Though, proposal was made to combine these syndromes in the past, some subtle differences exist such as predominan...

January 2009 Version 9 TEMPORAL LOBE EPILEPSY: A CLINICAL VIEW POINT Background: Temporal lobe epilepsy (TLE) was defined in 1985 by the International League Against Epilepsy (ILAE) as a condition characterized by recurrent unprovoked seizures originating from the medial or lateral temporal lobe. The seizures associated with TLE consist of simple partial seizures without loss of awareness (with...

The prognosis of partial epilepsy in childhood (excluding cases of benign partial epilepsy) was studied; the average follow up period was 7.4 years. Improvement rate of seizure status was 82.3%. We studied favourable prognostic factors and found that those most often associated with seizure improvement were familial convulsions and idiopathic forms, no generalised seizures before partial onset,...

Epilepsy is one of the most common neurologic diseases around the world and more significantly in Iran (0.4-1 % worldwide and 5% in Iran). Almost one-third of these patients suffer from treatment-resistant epilepsy, which reduces their quality of life by recurring epileptic onsets. There are different approaches for the treatment of both treatment-resistant and treatment-nonresistant epilepsy, ...

We evaluated the potential clinical value of the Symptom Checklist-90-Revised (SCL-90-R) as a multidimensional self-report measure to identify the expected higher rates of clinically significant mental health symptoms in adults with partial/complex partial epilepsy (PE), as compared to a representative sample of adult non-patients. As expected, adults with PE had significantly higher rates of e...