In recent years, paraoxybenzoic acid esters (parabens) have been used in pharmaceuticals, cosmetics, and food additives. Parabens reported to a weak estrogenic effect vitro test systems, it is presumed that the longer alkyl chain of paraben, greater its endocrine-disrupting reproductive function effects. However, effects parabens on human health are still unclear. this study, we evaluated six (...

Parabens are esters of p-hydroxybenzoic acid and belong to group of effective preservatives commonly used in cosmetic products, drugs and food. Their antimicrobial activity increases with increasing carbon number of the ester group. A number of cosmetic products and skincare products are preserved with parabens, as well in Europe as in the United States. Methyl, ethyl and propyl paraben are pre...

Parabens are alkyl esters of p-hydroxybenzoic acid and are used as antimicrobial preservatives in a range of consumer products, including cosmetics, pharmaceuticals, and foodstuffs. Despite their widespread use, prior to this study, paraben concentrations in foodstuffs from China and human dietary exposure to these chemicals have been unknown. In this study, concentrations of six parabens were ...

mainly into semisolid formulations such as ointment, cream and lotion and dermal patches such as pressure sensitive adhesive tapes and cataplasma. These topical formulations contain many kinds of pharmaceutical additives. Alcohols, glycols, l-menthol, mineral and vegetable oils and surfactants as well as polymeric additives are prescribed for skin penetration enhancers, drug solubilizers, drug ...

BACKGROUND Personal care products (PCPs) are exposure sources to phthalates and parabens; however, their contribution to men's exposure is understudied. OBJECTIVES We examined the association between PCP use and urinary concentrations of phthalate metabolites and parabens in men. METHODS In a prospective cohort, at multiple study visits, men self-reported their use of 14 PCPs and provided a...

BACKGROUND Parabens are commonly used as antimicrobial preservatives in cosmetics, pharmaceuticals, and food and beverage processing. Widespread human exposure to parabens has been recently documented, and some parabens have demonstrated adverse effects on male reproduction in animal studies. However, human epidemiologic studies are lacking. OBJECTIVE We investigated relationships between uri...

Parabens, benzophenone-3 (BP3), and phthalates are commonly used as antimicrobial conservator, UV-filter, and plasticizer, respectively, and are thought to exhibit endocrine disrupting properties. These endocrine disrupting activities have been recently assumed to lead to cutaneous malignant melanoma. Humans are exposed to these chemicals through different sources such as food, personal care pr...

BACKGROUND Exposure to environmental phenols (e.g., bisphenol A, benzophenone-3, and triclosan) and parabens is widespread in the population. Many of these chemicals have been shown to have anti-androgenic effects both in vitro and in vivo. OBJECTIVE We examined the association of bisphenol A (BPA), benzophenone-3 (BP-3), triclosan (TCS), and parabens with serum total testosterone (TT) levels...

Abstract Context Parabens are used as preservatives in consumer products but suspected of having endocrine-disrupting properties. A recent study reported an association between utero exposure to butyl paraben and overweight childhood, with a stronger trend girls. Objective We therefore studied the parabens maternal urine third trimester fat percentage children aged 7 years. Design, Setting, Par...

Parabens are widely used in different industries as preservatives and antimicrobial compounds. The evolution of analytical techniques allowed the detection these compounds sources at µg/L ng/L. Until today, parabens were already found water sources, air, soil even human tissues. impact humans, animals ecosystems a matter discussion within scientific community, but it is proven that can act endo...