The geographical relationship of saponin composition of Panax species has been studied extensively. Close similarity in saponin composition was observed for the plants in Eastern Himalaya, South-western China and Southern Japan. The exeptional saponin compositions were found for some plants growing near the western and southern limits of the distribution as well as that in Japan Island. Compari...

Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L.) are the two most recognized ginseng botanicals. It is believed that the ginseng saponins called ginsenosides are the major active constituents in both ginsengs. Although American ginseng is not as extensively studied as Asian ginseng, it is one of the best selling herbs in the U.S., and has garnered increasing attention...

Ginseng is the root of the perennial herbs of Panax quinquefolium and Panax ginseng which contain a series of tetracyclic triterpenoid saponins (ginsenosides) as active ingredients. It is considered a tonic or adaptogenic that enhances physical performance (including sexual), promotes vitality and increases resistance to stress and ageing. The adaptogenic properties of ginseng are believed to b...

Breast cancer is the most frequently diagnosed form of cancer among women. Breast cancer is the leading cause of cancer death in nearly all developed countries, showing an increased incidence over the last decades, and the expected number of new U.S. patients in 2010 would be 209,060, and the death number will be 40,230 1. The clinical management of breast cancer invariably involves diverse con...

Invited Review: Ginseng is actually a collection of 11 distinct species of slow-growing perennial plants with fleshy roots, but Panax ginseng C.A. Meyer (Araliaceae) or Korean ginseng is the main one. The root of P. ginseng is a traditional medicine in Korea, China and Japan that has been shown to produce a variety of medicinal effects. The reported pharmacological activities of ginseng and its...

introduction: the fate of xenobiotics that is present, increasing day by day. the increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. methods: the present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by panax ginseng ...

BACKGROUND Food adulteration remains a major global concern. DNA fingerprinting has several advantages over chemical and morphological identification techniques. DNA microarray-based fingerprinting techniques have not been used previously to detect adulteration involving dried commercial samples of closely related species. Here we report amplification of low-level DNA obtained from dried commer...

In the present study the adaptogenic activities of the saponin fractions of the leaves and roots of Polyscias fruticosa (L) Harms (Araliaceae) were studied in comparision wit white panax ginseng root saponins. The antibacterial activity of the polyacetylenic compound in leaves were also studied. The adaptogenic activity studies showed that polyscias fruticosa leaf and root saponins have effecti...

OBJECTIVE In this open trial, Panax ginseng, a serotonin and norepinephrine reuptake inhibitor, actually used as an antidepressant, has been investigated for its efficacy in the treatment of attention-deficit hyperactivity disorder (ADHD) patients. METHOD Three 14-17-year-old male psychiatric outpatients, diagnosed with ADHD disattention type have been rated at baseline and while taking Panax...

Cyclophilins (CyPs), a member of peptidyl-prolyl cis-trans isomerases (PPIases), are ubiquitously distributed in organisms such as bacteria, yeast, plants and animals. CyPs have diverse biological functions, with some exhibiting antifungal and antiviral activities. In this study, Panax ginseng cyclophilin (pgCyP), a novel gene encoding an antifungal protein from Panax ginseng, was cloned, and i...