AIMS The palatability of a new paediatric formulation of valaciclovir was assessed in children and their parents: non-inferiority of the new paediatric formulation (test formulation) compared to the reference formulation was investigated. METHODS In vivo palatability testing was performed in a randomized, two-period, multicentre, cross-over study. Children and their parents scored the liking ...

BACKGROUND Hydrolyzed formulas used to feed infants with cow's milk-allergy can be classified as soy based, extensively hydrolyzed (casein, whey and mixed), and amino-acid based. Their unsatisfactory taste is reported by parents and physicians. OBJECTIVE The aim of this study was to ascertain the palatability of these formulas in a double-blind taste test. MATERIALS AND METHODS Fifty health...

Dama wallabies (Macropus eugenii) are considered significant pests in the Bay of Plenty. FeraCol, a possum control product, was tested for palatability and efficacy on eight penned male dama wallabies. FeraCol had very low palatability to captive wallabies. Only one wallaby ate a lethal dose, and it died 4 days later. FeraCol, in its present form, would be unsuitable for controlling dama wallab...

There is an increased need for highly palatable oral dosage forms for dogs and cats, especially in the case of regular or chronic medications. To meet this need of easy application, the original Drontal® Plus tablet, a broad-spectrum anthelminthic, was optimized using a novel formula. A field study was conducted to evaluate the palatability of this new Drontal® Plus formula in comparison to a p...

Current theories of plant-herbivore interactions suggest that plants may differ in palatability to herbivores as a function of abiotic stress; however, studies of these theories have produced mixed results. We compared the palatability of eight common salt marsh plants that occur across elevational and salinity stress gradients to six common leaf-chewing herbivores to determine patterns of plan...

Previous studies have shown that rats' positive, palatability-dependent consummatory reactions to infused tastes are selectively facilitated by a benzodiazepine agonist (chlordiazepoxide), and that this effect can be blocked by the coadministration of benzodiazepine antagonists (e.g., Ro 15-1788). The purpose of the present study was to determine whether agents acting at other receptor sites (d...

BACKGROUND Hyperkalemia is a potentially life-threatening condition that patients with heart failure or chronic kidney disease, especially those taking renin-angiotensin-aldosterone system inhibitors, are at high risk of developing. Sodium polystyrene sulfonate (SPS), a current treatment, binds potassium within the gastrointestinal tract to reduce potassium absorption. However, poor palatabilit...

Long-standing theory predicts that the intensity of consumer-prey interactions declines with increasing latitude, yet for plant-herbivore interactions, latitudinal changes in herbivory rates and plant palatability have received variable support. The topic is of growing interest given that lower-latitude species are moving poleward at an accelerating rate due to climate change, and predicting lo...

Assessment of canine palatability is important for both the pet food and pharmaceutical industries; however, the current palatability assessment protocols are limited in their utility. The most common technique, the two-pan test, does not control for the satiating effects of food and may not be useful for long-term palatability analysis because nutritional or caloric characteristics of the diet...

While sodium reduction in the diet is an important objective, when salt (NaCl) levels are reduced in foods, its palatability is also generally decreased. Monosodium glutamate (MSG) is a flavour enhancer that contains about 12% sodium, which is less than half of that contained in regular table salt at about 39%. Therefore, by the addition of an appropriate amount of MSG, the palatability of low ...