accepted, more obvious evidence is needed. In PPI, return of colonic motility is a hindmost concern; it takes 48 to 72 hours. Sham feeding enhances gastric emptying and increases rectosigmoid pressure activity. However, the influence of gum chewing on colonic motility is not clear. Alvimopan, a peripherally-acting μ-opioid receptor antagonist, was recently approved for the reduction of PPI afte...