The geometrical and quantum mechanical basis for Davies' and Unruh's acceleration temperature is traced to a type of quantum mechanical (\achronal") spin. Its existence and deenition are based on pairs of causally disjoint accelerated frames. For bosons the expected spin vector of monochromatic particles is given by the \Planckian power" and the \r.m.s. thermal uctuation" spectra. Under space-t...

The histopathological diagnosis of Alzheimer's disease relies on two kinds of proteinaceous aggregates: the extracellular plaques built from filaments of the Abeta-peptide and the intracellular tangles consisting of tau polymerized into Paired Helical Filaments (PHFs). The order of aggregation events is still under debate, but it is well accepted that tau-related changes have an important impac...

The tau protein is a neuronal microtubule-associated protein. Apart of its physiological function-the binding to and stabilization of microtubules-tau is found in Alzheimer's disease brain as insoluble fibers, the so-called "paired helical filaments" (PHFs). Investigating the fundamentals of tau polymerization is indispensable for identifying inhibitory conditions or compounds preventing PHF fo...

the acquisition of argument structures has been studied by a variety of second language acquisition scholars within the past two decades (atay, 2010; can, 2009; chay, 2006, & kras, 2007, among others). in the present study, ‘predicate’ as the most substantial element of a sentence is investigated. there are three english verb-types which seem to be more problematic for persian efl learners:...

A dominating set of a graph is a vertex subset that any vertex belongs to or is adjacent to. Among the many well-studied variants of domination are the so-called paired-dominating sets. A paired-dominating set is a dominating set whose induced subgraph has a perfect matching. In this paper, we continue their study. We focus on graphs that do not contain the net-graph (obtained by attaching a pe...

The evolution of the writing machine from early eighteenth-century concepts to the modern electronic typewriter represents a rich history of innovative efforts by many individuals in several countries. This paper briefly highlights several significant early milestones and then draws particular attention to typewriter developments within the IBM Corporation. After entering the typewriter busines...

We define a ranked trigroupoid as a natural followup on the idea of a ranked bigroupoid. We consider the idea of a derivation on such a trigroupoid as representing a two-step process on a pair of ranked bigroupoids where the mapping d is a self-derivation at each step. Following up on this idea we obtain several results and conclusions of interest. We also discuss the notion of a couplet (D, d)...

Furin inhibitors are promising therapeutics for the treatment of cancer and numerous infections caused by bacteria and viruses, including the highly lethal Bacillus anthracis or the pandemic influenza virus. Development and improvement of inhibitors for pharmacological use require a detailed knowledge of the protease's substrate and inhibitor binding properties. Here we present a novel preparat...