: This study aimed to evaluate effect of pre-gynecological examination counselingsessions on relieving women’s pain, discomfort, and enhancing their satisfaction.

Bone cancer pain is the most severe among cancer pain and is often resistant to current analgesics. Thus, the development of novel analgesics effective at treating bone cancer pain are desired. Platelet-activating factor (PAF) receptor antagonists were recently demonstrated to have effective pain relieving effects on neuropathic pain in several animal models. The present study examined the pain...

Acetaminophen, also known as APAP or paracetamol, is one of the most widely used analgesics (pain reliever) and antipyretics (fever reducer). According to the U.S. Food and Drug Administration, currently there are 235 approved prescription and over-the-counter drug products containing acetaminophen as an active ingredient. When used as directed, acetaminophen is very safe and effective; however...

OBJECTIVE To evaluate the literature on the effectiveness of aquatic exercise in relieving pain in adults with neurologic or musculoskeletal disease. DATA SOURCES A systematic literature search of 14 databases was examined for research on aquatic exercise over the period January 1980 to June 2006. STUDY SELECTION Randomized controlled trials (RCTs) that included adults with neurologic or mu...

OBJECTIVES To test the comparative effectiveness of 2 nonpharmacologic pain-relieving interventions administered alone or in combination across time for repeated heel sticks in preterm infants. METHODS A multicenter randomized controlled trial in 3 NICUs in Switzerland compared the effectiveness of oral sucrose, facilitated tucking (FT), and a combination of both interventions in preterm infa...

Pain is aversive, and its relief elicits reward mediated by dopaminergic signaling in the nucleus accumbens (NAc), a part of the mesolimbic reward motivation pathway. How the reward pathway is engaged by pain-relieving treatments is not known. Endogenous opioid signaling in the anterior cingulate cortex (ACC), an area encoding pain aversiveness, contributes to pain modulation. We examined wheth...

Received March 28, 2013. Accepted April 18, 2013. Correspondence to: Mohamed Amin Ghobadifar, MD Department of Student Research Committee, Medicine School, Jahrom University of Medical Sciences, Motahari Avenue, Jahrom, Iran Tel: +98-936-620-8078, Fax: +98-711-636-13-86, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution No...

To study the efficacy of electro-acupuncture for the relief of labor pain, and to build a better understanding of how electro-acupuncture might influence the neuroendocrine system, 36 primiparas were randomly divided into an electro-acupuncture group and a control group. Assessments of pain intensity and degree of relaxation during labor were analyzed. The differences between the electro-acupun...

introduction: pemphigus vulgaris (pv) is a chronic, serious autoimmune mucocutaneous bullous disease. oral lesions in pv may be extremely painful. this pain may adversely affect the patients’ oral intake and quality of life. this before-after clinical trial was designed to assess the pain relieving effects of single session of non-ablative, non-thermal co2 laser therapy (ntclt) in oral lesions ...