Paecilomyces sp. is a saprophytic fungus which has rarely been associated with human disease. We report the first case of invasive subcutaneous infection caused by this fungus in a 78-year-old female from Damghan, Iran, with diabetes and chronic renal failure. A biopsy provided an initial diagnosis of the mold in tissue. Multiple positive fungal cultures which were obtained from the biopsied ti...

paecilomyces sp . are saprophytic fungi, which have rarely been pathogen for human. herein, we report a case of cutaneous infection with paecilomyces lilacinus with unusual presentations in a healthy young woman. a biopsy provided an initial diagnosis of fungal elements in the tissue. multiple positive fungal cultures were obtained from the biopsied tissue. microscopic and macroscopic examinati...

We evaluated the performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), the MALDI Bruker Biotyper system (microflex LT; Bruker Daltonik GmbH, Bremen, Germany), on the identification of 50 isolates of clinically encountered molds, including Penicillium marneffei (n = 28), Paecilomyces species (n = 12), Fusarium solani (n = 6), Rhizopus species...

This study reports the antibacterial activity of an oligosaccharide, prepared by partial acid hydrolysis of a native Paecilomyces sp. exopolysaccharide, and of its aminoglycosylated derivative, prepared by reductive alkylation of the oligosaccharide, against E. coli and S. aureus.

Paecilomyces Sp. are saprophytic fungi, which have rarely been pathogen for human. Herein, we report a case of cutaneous infection with Paecilomyces lilacinus with unusual presentations in a healthy young woman. A biopsy provided an initial diagnosis of fungal elements in the tissue. Multiple positive fungal cultures were obtained from the biopsied tissue. Microscopic and macroscopic examinatio...

Paecilopeptin, a novel cathepsin S inhibitor, was produced and isolated from the culture supernatant of the fungal strain, Paecilomyces carneus. A spectroscopic analysis revealed the planar structure of paecilopeptin to be acetyl-Leu-Val-CHO. The stereochemistry of the constituent amino acids was analysed by chiral HPLC after oxidation and 6N HCl hydrolysis of paecilopeptin. The total synthesis...

A 61-year-old hypertensive woman on continuous ambulatory peritoneal dialysis (CAPD) with a swan neck Tenckhoff catheter for the past 2 years undergoing four exchanges/day, and on anti-tuberculous treatment presented with poor drainage of the dialysate effluent for 5 days. At presentation, a cheesy material was seen in the catheter with cloudy effluent and poor inflow–outflow. The exit site and...