Introduction Pachydermoperiostosis is a syndrome characterized by finger clubbing, periosteal new bone formation especially over the distal ends of long bones, and coarsening of the facial features, with thickening, furrowing and oiliness of the skin of the face and forehead. The first reported cases were the Hagner brothers, who had typical features of this syndrome. They were first described ...

To cite: Chakraborty PP, Bhattacharjee R, Mukhopadhyay S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016214624 DESCRIPTION A 19-year-old male patient presented with a yearlong history of progressive painful enlargement of his hands and feet associated with excessive sweating and greasiness of the face, palms and soles. He also noticed pain over his wr...

Pachydermoperiostosis is a rare hereditary disease, which presents with the cutaneous manifestations of pachydermia and cutis verticis gyrata. Histological findings in pachydermia frequently include dermal edema, mucin deposition, elastic fiber degeneration, dermal fibrosis and adnexal hyperplasia. However, the severity of these findings varies between clinical reports, and a systematic multipl...