Telomeres are repeating DNA at chromosome ends. Telomere length (TL) declines with age in most human tissues, and shorter TL is thought to accelerate senescence. In contrast, older men have sperm with longer TL; correspondingly, older paternal age at conception (PAC) predicts longer TL in offspring. This PAC-effect could be a unique form of transgenerational genetic plasticity that modifies som...

Rice-rapeseed relay cropping is an effective way to use winter fallow fields and increaseland use efficiency. However, the overlapping period of 10–15 days for rice-rapeseedcultivation results in reduced winter survival and less yields. Therefore, in this study, weinvestigated if the treatment of oil rape seeds with paclobutrazol (PAC) improves its winterhardiness and yields by altering its cro...

We present a PAC-Bayes-Empirical-Bernstein inequality. The inequality is based on a combination of the PAC-Bayesian bounding technique with an Empirical Bernstein bound. We show that when the empirical variance is significantly smaller than the empirical loss the PAC-Bayes-Empirical-Bernstein inequality is significantly tighter than the PAC-Bayes-kl inequality of Seeger (2002) and otherwise it ...

We examined the natural organic matter (NOM) adsorption characteristics of super-powdered activated carbon (S-PAC) produced by pulverizing commercially available, normal PAC to a submicron particle size range. The adsorption capacities of S-PAC for NOM and polystyrene sulfonates (PSS) with molecular weights (MWs) of 1.1, 1.8, and 4.6 kDa, which we used as model compounds, were considerably high...

BACKGROUND Lung transplantation (LTx) is a therapy for patients with cystic fibrosis (CF) end-stage lung disease. Pseudomonal airway colonization (PAC) is common in CF. OBJECTIVES We investigated the influence of post-transplant sinus surgery and daily nasal douching on PAC after LTx and the influence of PAC on survival and bronchiolitis obliterans syndrome (BOS). METHODS CF patients transp...

The effect of SecB chaperone on production of periplasmic penicillin acylase (PAC) in Escherichia coli was investigated. It appears that formation of PAC required the function of SecB chaperone and the amount of SecB required was at a basal level. The secB mutant was defective in production of PAC, and the impairment could be complemented by extrachromosomally supplementing SecB in trans. The f...

BACKGROUND Totally implanted access ports (PACs) are valuable tools for the treatment of patients with cancer because they ease the administration of chemotherapy, stem cells, and supportive care by reducing the rate of peripheral vein punctures. OBJECTIVES The purpose of this study was to evaluate the satisfaction and impairments of activities of daily living of ambulatory patients with PAC ...

In this lecture we will talk about the PAC model. The PAC learning model is one of the important and famous learning model. PAC stands for Probably Approximately Correct, our goal is to learn a hypothesis from a hypothesis class such that in high con dence we will have a small error rate (approximately correct). We start the lecture with an intuitive example to explain the idea behind the PAC m...

PURPOSE/OBJECTIVES To identify changes in positive aspects of care (PAC) from the time of diagnosis to four months following the diagnosis in family caregivers of care recipients with primary malignant brain tumors. DESIGN Longitudinal. SETTING Dyads were recruited from neurosurgery clinics in Pittsburgh, PA, at the time of care recipients' diagnosis with a primary malignant brain tumor. A ...

Streptococcus mutans is the primary etiological agent of dental caries. The antimicrobial peptide D-Nal-Pac-525 was designed by replacing the tryptophans of the Trp-rich peptide Pac-525 with D-β-naphthyalanines. To assess the effect of D-Nal-Pac-525 on cariogenic bacteria, the activity of D-Nal-Pac-525 on the growth of S. mutans and its biofilm formation were examined. D-Nal- Pac-525 showed rob...