نتایج جستجو برای: p rosolic acid ra

تعداد نتایج: 1943974  

2016
Hans Vergauwen Sara Prims Jeroen Degroote Wei Wang Christophe Casteleyn Steven van Cruchten Stefaan de Smet Joris Michiels Chris van Ginneken

Oxidative stress in the small intestinal epithelium can lead to barrier malfunction. In this study, the effect of rosmarinic acid (RA), quercetin (Que), gallic acid (GA), lipoic acid (LA), ethoxyquin (ETQ) and Se-methionine (SeMet) pre-treatments using 2 mM Trolox as a control on the viability and the generation of intracellular reactive oxygen species (iROS) of oxidatively (H₂O₂) stressed inte...

Journal: :Journal of ethnopharmacology 2011
Zhiyi Qiang Zhong Ye Cathy Hauck Patricia A Murphy Joe-Ann McCoy Mark P Widrlechner Manju B Reddy Suzanne Hendrich

ETHNOPHARMACOLOGICAL RELEVANCE Rosmarinic acid (RA), a caffeic acid-related compound found in high concentrations in Prunella vulgaris (self-heal), and ursolic acid (UA), a pentacyclic triterpene acid concentrated in Salvia officinalis (sage), have been traditionally used to treat inflammation in the mouth, and may also be beneficial for gastrointestinal health in general. AIM OF THE STUDY To...

Journal: :Food & function 2015
Ying Zhang Xiaoqiang Chen Lei Yang Yuangang Zu Qi Lu

Rosmarinic acid (RA), which is a natural polyphenol, was isolated from Rosmarinus. officinalis L. The aim of this study is to evaluate the effects of rosmarinic acid on liver and kidney antioxidant enzymes and the tissue ultrastructure in aging mice. RA was administrated at a dosage of 50, 100 or 200 mg kg(-1) once a day with a normal control group and an aging control group for 30 days. The li...

2017
Yehua Rui Lingxia Tong Jinbo Cheng Guiping Wang Liqiang Qin Zhongxiao Wan

Background: Rosmarinic acid (RA) is a natural phenol carboxylic acid with many promising biological effects. It may be a suitable candidate for improving obesity-related adipose tissue dysfunction. Objective: We aimed to investigate the therapeutic use of RA as an anti-obesity agent by measuring its effects on adipogenesis, lipolysis, and messenger RNA (mRNA) expression of major adipokines in 3...

2017
Yu-Ju Wen Mei-Chin Yin

BACKGROUND Rosmarinic acid (RA) is a polyphenol present in members of the Lamiaceae family. In this study, yhe anti-inflammatory and anti-glycative effects of RA in the livers of type 1 diabetic mice were examined. METHODS The diabetic mice were divided into three groups: diabetic mice with 0, low dose RA (25 mg/ml), and high dose RA (50 mg/ml). One group of non-diabetic mice was used as a co...

Journal: :cell journal 0

objective: retinoids are recognized as important regulators of cell differention and tissue function. previous studies, performed both in vivo and in vitro, indicate that retinoids influence several reproductive events. in this study, we investigated the effect of all-trans retinoic acid (t-ra) on maturation and fertilization rate of immature oocytes (germinal vesicle). materials and methods: g...

Gout and rheumatoid arthritis (RA) are relatively common diseases however, the coexistence of these two conditions has been rarely reported. The author presents a case that was followed for 20 years as RA and gout was also diagnosed based on nodular lesion on feet joints, tap nodules and noticing crystals of uric acid in synovial fluid. In RA patients with severe joint swelling, physicians shou...

Journal: :cell journal 0

introduction: eugenol (eg), a compound extracted from clove tree, is known for its anti- anaphylactic, anti-inflammation, antiseptic, antibacterial and analgesic properties as well as chain breaking antioxidant in inhibition of lipid peroxidation. retinoic acid (ra), one of the synthetic derivatives of vitamin a, has been frequently used for treatment of face acne. in our studies eg was used to...

1999
ROBERT E. SHANGRAW FAROOK JAHOOR

Shangraw, Robert E., and Farook Jahoor. Effect of liver disease and transplantation on urea synthesis in humans: relationship to acid-base status. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G1145–G1152, 1999.—It has been suggested that hepatic urea synthesis, which consumes HCO3 , plays an important role in acid-base homeostasis. This study measured urea synthesis rate (Ra urea) dir...

Journal: :Circulation research 2001
V Haxsen S Adam-Stitah E Ritz J Wagner

Retinoids are derivatives of vitamin A and powerful inhibitors of cell proliferation and inflammation. Angiotensin II (Ang II) contributes to vascular lesions by promoting cell growth of vascular smooth muscle cells (VSMCs). Therefore, we examined whether retinoids interfere with the proproliferative actions of Ang II in VSMCs via AT(1) receptor-dependent or activator protein-1 (AP-1)-dependent...

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