Miniature postsynaptic currents (minis) in cultured retinal amacrine cells, as in other central neurons, show large variations in amplitude. To understand the origin of this variability, we have exploited a novel form of synapse in which pre- and postsynaptic receptors sample the same quantum of transmitter. At these synapses, mini amplitudes measured simultaneously in the 2 cells show a strong...

The purpose of this paper is to research the ways integrating sustainable development into study programs engineering faculties in an international con-text, as well analyse current state education for at universities Republic Serbia. Therefore, a desk-top research, analysis curricula, have been conducted. results indicated two possible approaches integration curricula ? form special subjects d...

A ni-:\v science has arisen of recent years in topical medicine, and is rapidly coming to the front; that of medical mycology. Many of the skin diseases of the tropics are due to infection with fnngi, and recent articles by Lt.-Col. H. w. Acton, i.M.S., and his assistants, Dr. C. McGuire, Dr. Ganapati Panja and Dr. Iv. P. Banner ji, show how important this infection is ln gen?rah medical practi...

Information transfer at neuronal synapses requires rapid fusion of docked synaptic vesicles in response to calcium influx during action potentials. The molecular nature of the fusion clamp machinery that prevents exocytosis of synaptic vesicles in the absence of a calcium signal is still unclear. Here we show that complexin, a small alpha-helical protein that binds fully assembled SNARE complex...

Background: This study aims to explore the relevance and utilization of CA 72.4 tumor marker in cancer diagnosis, with a particular focus on gastrointestinal tumors ovarian cancer, based data from Minis-try Health. Materials Methods: We conducted retrospective analysis health records Ministry Health spanning over five years. The data, consisting various demographics, including gender, age, clin...

Abstract Colour is one of the most important phenotypic characters table grape cultivars, which has high importance in consumer's preference. This morphological trait variable and not consistently uniform within a cultivar or even bunch. Between harvest consumption fruits are stored for several weeks time influencing colour berry. In this study 10 grapevine accessions (Agaphante, KM98, Korai pi...

The Monograph is the result of scientific and practical cooperation Ministry Defense Ukraine, General Staff Armed Forces Command Medical Forces, Ukrainian Military Academy, SE “L.I. Medveds Research Center Preventive Toxicology, Food Chemical Safety Health Ukraine”, State University “Na-tional Scientific Radiation Medicine National Academy Sci-ences Ukraine” in field radioprotection, namely - p...

Action potential-independent “miniature” synaptic events have a long tradition in electrophysiology as helpful tools to investigate the quantal properties and plasticity mechanisms of synaptic transmission (Katz 1969). Since the introduction of high-resolution whole cell patch clamping in brain slices (Edwards et al. 1990), mini analysis has also been employed in epilepsy research, primarily to...

An Aplysia motor neuron cocultured with a single presynaptic sensory neuron exhibits spontaneous miniature EPSPs or EPSCs ("minis") that can be used to assay the release process directly, independent of the presynaptic action potential. Sensory-motor synapses in culture undergo homosynaptic depression with low frequency stimulation (< 1 Hz) and posttetanic potentiation (PTP) with high-frequency...

Broad amplitude variability and skewed distributions are characteristic features of quantal synaptic currents (minis) at central synapses. The relative contributions of the various underlying sources are still debated. Through computational models of thalamocortical neurons, we separated intra- from extra-synaptic sources. Our simulations indicate that the external factors of local input resist...