Between May 1988 and June 2000, 698 children were treated in the Medical Research Council acute myeloid leukemia 10 and 12 trials. The presenting features and outcomes of therapy in these children were compared by age. Although there was no single cutoff in age, younger children were more likely to have intermediate risk and less likely to have favorable cytogenetics (P <.001), and they had a h...

BACKGROUND The purpose of this retrospective study was to develop a two- and three-dimensional analysis of the airway using cone-beam computed tomography (CBCT) and to determine whether the airway space would be changed in mandibular prognathism after bimaxillary surgery involving maxillary posterior impaction. METHODS Patients requiring orthognathic surgery from 2012 to 2014 were recruited f...

Context.\p=m-\Themain threats to adolescents' health are the risk behaviors they choose. How their social context shapes their behaviors is poorly understood. Objective.\p=m-\Toidentify risk and protective factors at the family, school, and individual levels as they relate to 4 domains of adolescent health and morbidity: emotional health, violence, substance use, and sexuality. Design.\p=m-\Cro...

Sleep disturbance is a very common problem for cancer patients that has largely not been addressed in the clinical intervention literature. Mindfulness meditation has demonstrated clinical benefits for a variety of patient populations in other areas of functioning. This study examined the effects of an 8-week Mindfulness-Based Stress Reduction (MBSR) program on the sleep quality of a heterogene...

were analysed for wet and dry weight, total lipid, total, free and esterified cholesterol, total carboxyl ester, lipid phosphorus and triglyceride. The translocated testes decreased in wet and dry weight (P<0\m=.\001) and total lipid content (P< 0\m=.\001)6 days after surgery. Lipid concentration increased (P<0\m=.\01)in translocated testes, as did concentrations of total cholesterol (P<0\m=.\0...

OBJECTIVE To evaluate the effects of educational and psychological intervention on the quality of life and psychological status of patients with asthma. METHODS Asthmatic patients were randomized to study (n = 228) and control (n = 146) groups. Both groups received conventional pharmacotherapy for asthma. The study group also received education and psychological counseling. We assessed qualit...

This study investigated the feasibility and reliability of a 12 × 25-m repeated sprint test with sprints starting every 25-s in children aged 6-8 years (36 boys, 41 girls). In all subjects, total sprint time (TST) demonstrated high test-retest reliability (ICC: r = .98; CV: 0.7% (95% CI: 0.6-0.9)). While sprint time varied over the 12 sprints in all subjects (p < .001) with a significant increa...

BACKGROUND We conducted a study to evaluate the impact of education and an antibiotic-control program on antibiotic-prescribing practices, antibiotic consumption, antimicrobial resistance, and cost of antibiotics in a tertiary care hospital in Thailand. METHODS A study of the year before and the year after the intervention was performed. Inpatient antibiotic prescriptions were prospectively o...

To evaluate the effect of thermocycling on water contact angle (WCA), surface roughness (SR), and microhardness (MH) different CAD-CAM PMMA denture base materials after treatments (conventional laboratory polishing, polishing kit, or sealant). Disk-shaped specimens (10 × 2 mm) 3 PMMAs, AvaDent (AV); Merz M-PM (M-PM); Polident (Poli), a conventional heat-polymerized (Vynacron) (CV) (n=21) were d...