A method has been developed for the synthesis of semicrystalline poly(arylene ether ether sulfide) materials by first preparing a soluble, amorphous sulfoxide containing precursor, then rapidly reducing the sulfoxide moiety to sulfide. The sulfoxide polymers are synthesized using conventional nucleophilic aromatic substitution reactions between difluorodiphenyl sulfoxide and diphenols. Reductio...

A simple and reliable method, based on that described by W. Seubert (1960, Biochem Prep. 7, 80-83), has been developed for the chemical synthesis of radioactive acyl coenzyme A’s. I-14C-labeled fatty acids (palmitic, oleic, and linoleic) are converted to their acyl chlorides with oxalyl chloride. The [l-14C]acyl chlorides are then condensed with a twoto three-fold molar excess of coenzyme A in ...

New Schiff bases, hydrazones and semicarbazones derived from 1,2-dihydro-4-hydroxy-6-methyl2-oxoquinoline-3-carbaldehyde, have been synthesized. The semicarbazone was subjected to react with 2,3-dichloroquinoxaline, chloroacetic acid, and oxalyl chloride affording multiaza­ heterocycles substituted to quinolone moiety at position 3. Condensation of the 2-imidazolidinethione derivative with some...

A mild and convenient one-step preparation of 4H-1,3-benzoxazin-4-ones by a domino carbonylation-cyclization process is developed. Readily available ortho-iodophenols are subjected to palladium-catalyzed carbonylative coupling with Mo(CO)6 and cyanamide, followed by a spontaneous, intramolecular cyclization to afford 4H-1,3-benzoxazin-4-ones in moderate to excellent yields. Furthermore, the sco...