Solid epididymal masses can be broadly classified into three categories: inflammatory mass, benign neoplasm, and malignant neoplasm. Examples of inflammatory processes include infectious epididymitis, fibrosis, sperm granuloma, and autoimmune disease. Benign neoplasms include adenomatoid tumor or leiomyoma. Malignant neoplasms include adenocarcinoma, embryonic rhabdomyosarcoma, and seminoma. Wh...

Mice overexpressing the prion protein (PrP) sequence from various host species are widely used for measuring infectious titers in prion disease. However, the impact that the transgene expression level might have on the susceptibility to infection raises some concerns about the final biological relevance of these models. Here we report that endpoint titration of a sheep scrapie isolate in sheep ...

In an 18 month period, 198 men presented with a painful, swollen, and tender epididymis or testicular or scrotal pain. Fifty were excluded from analysis because of prior antibiotic treatment or a history of the disease, or both. Of the remaining patients, epididymitis was not diagnosed in 108, though 23 (21%) of them had urethritis. Thus 40 men were seen who had acute unilateral epididymitis. O...

Twelve slow-growing virus isolates propagated in tissue culture from cattle with epididymitis and vaginitis were identified as herpes viruses by virtue of their biological, physicochemical and morphological characteristics. None of the 12 virus strains proved to be serologically related to the infectious pustular vulvo-vaginitis-infectious bovine rhinotracheitis (IPV-IBR) virus, but a further 3...

Xanthogranulomatous epididymitis is a rare benign process with destruction of tissue and replacement by cellular infiltration foamy macrophages, dense lymphocytes plasma cells. Literature has very few case reports. We reported here 72 years old male who presented as scrotal abscess bilateral hydrocele on ultrasound. On exploration he had normal right testis localized to epididymis underwent epi...

Tuberculous epididymitis is a rare urological disease difficult to diagnose. The conventional methods for diagnosis are often time-consuming and invasive. The combined use of scrotal magnetic resonance imaging (MRI) and urinary polymerase chain reaction (PCR)-based assay for mycobacterial DNA (the latter because of its high sensitivity and specificity to demonstrate mycobacterial DNA) is a valu...

Ovine interferon-gamma (IFN-γ) cDNA was isolated from total mRNA of peripheral blood mononuclear cells from indigenous sheep by reverse transcription PCR. The cDNA was successfully cloned, sequenced and expressed in Escherichia coli as thioredoxin fusion protein. Sequence comparison of Indian sheep IFN-γ showed high nucleotide homology with published IFN-γ sequences of sheep and other species o...