BACKGROUND To investigate the relationship between depression and overactive bladder (OAB)/urinary incontinence symptoms among the clinical OAB population. METHODS Patients who were diagnosed with overactive bladder (OAB) and age-matched control subjects without OAB were enrolled. Depression symptoms were assessed using the Hospital Anxiety and Depression Scale (HADS-D). OAB/incontinence symp...

PURPOSE To determine whether levels of nerve growth factor (NGF) and heparin-binding epidermal growth factor-like growth factor (HB-EGF) can be used to objectively assess overactive bladder syndrome (OAB) treatment outcome and to evaluate the effects of fixed-dose fesoterodine on OAB symptoms. MATERIALS AND METHODS This study included 124 participants (62 patients with OAB and 62 controls) in...

The overactive bladder (OAB) is a debilitating condition in which patients suffer from urinary urgency, frequency and nocturia with or without urge urinary incontinence. The mainstay of pharmacotherapy for OAB is muscarinic receptor antagonists, which have been shown to be effective treatments for the symptoms of OAB. The mechanism underlying the efficacy of antimuscarinic agents against the sy...

PURPOSE This study was to investigate whether a systematized bladder training (BT) program is effective for patients with idiopathic overactive bladder (OAB). METHODS A prospective study was conducted on 105 patients with OAB from March 2009 to November 2011. We developed a 30 minutes BT program, which consisted of first, refraining from going to the bathroom after feeling an urge to void, se...

Overactive bladder (OAB) syndrome occurs when the bladder contracts suddenly without the individual’s control or when the bladder is not full. Symptoms of OAB include a sudden urgent desire to pass urine (urgency), going to the toilet often (frequency), waking up to use the toilet more than once at night (nocturia), and the passing of small quantities of urine before a toilet can be reached whe...

OBJECTIVE To compare bladder wall thickness (BWT) between female patients with overactive bladder (OAB) and aged-matched healthy controls. MATERIAL AND METHODS Thirty-six female patients with OAB and 31 healthy women were enrolled in the present prospective observational study. Qmax and Qave were measured by using uroflowmetry in all of the women in the patient and control groups, and also ma...

Hypothesis / aims of study Overactive bladder (OAB) associated with bladder outlet obstruction (BOO) is common in elderly men. However, its exact etiology remains unclear. Tamsulosin is an α1-adrenoceptor blocker used in the treatment of symptomatic benign prostatic hyperplasia worldwide, and known to be effective for OAB as well as obstructive symptoms. In this study, we investigated the effec...

PURPOSE We assess the prevalence of overactive bladder (OAB) and its risk factors in a male urologic veterans population. MATERIALS AND METHODS Validated self-administered questionnaire was prospectively given. RESULTS Among 1086 patients, OAB was present in 75%, of which 48% had not been diagnosed/treated. The risk of OAB increased with age. OAB was not associated with BMI, smoking, race, ...

Overactive bladder (OAB) is a prevalent and costly condition that can affect any age group. Typical symptoms include urinary urgency, frequency, incontinence and nocturia. OAB occurs as a result of abnormal contractions of the bladder detrusor muscle caused by the stimulation of certain muscarinic receptors. Therefore, antimuscarinic agents have long been considered the mainstay of pharmacologi...

PURPOSE Diabetes mellitus (DM) is a chronic metabolic disorder that often leads to complications. We aimed to correlate two complications of DM, polyneuropathy and hyperactive bladder syndrome, using noninvasive measures, such as screening tests. METHODS We included 80 female and 40 male type 2 diabetic patients in this prospective study. Diabetic polyneuropathy evaluations were conducted usi...